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Print 17 comment(s) - last by Cincybeck.. on Oct 2 at 7:12 PM

Researches on track to develop an artificial nose; no mouse backs involved.

The olfactory system is one of the oldest and definitely the most complex of a human's sensory equipment. It is not; however, anywhere near the most complex as far as Earth-based life goes.

A human's olfactory system is driven by about 400 active genes, which express proteins called olfactory receptors. By comparison, mankind's faithful canine companions have over 1,000 of these task specific genes dedicated to their sniffing abilities.

The complexity of the olfactory system has kept it one of the least understood biological systems. To compound this, olfactory proteins are remarkably difficult to study outside of the body as their composition makes them hydrophobic and causes them to lose their structure in water-based solutions.

A group at the Massachusetts Institute of Technology may have solved this problem of delicate structures. The project, known as MIT RealNose, MIT in this case representing microfluidic-integrated transduction, has been able to successfully harvest the proteins by utilizing a hydrophobic detergent solution, wheat germ extract and a multi-step purification process. The scientists were able to successfully produce enough of the protein structures via the process to begin functional and structural analysis.

“The main barrier to studying smell is that we haven't been able to make enough receptors and purify them to homogeneity,” explains MIT student Brian Cook. “Now, it's finally available as a raw material for people to utilize, and should enable many new studies into smell research.”

Understanding the nose and the developing the ability to build them from the bottom up may help produce better detection systems for anything from dangerous chemicals to medical conditions. A remotely operated artificial nose could replace bomb-sniffing dogs, keeping them and their partners out of harm's reach.



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o.0
By StevoLincolnite on 10/1/2008 7:53:18 AM , Rating: 2
I can imagine having ultra sensitive smell whilst in an elevator... *Shudders*




RE: o.0
By theapparition on 10/1/2008 7:54:12 AM , Rating: 2
Elevator???

Try a taxicab...........


RE: o.0
By ViroMan on 10/1/2008 8:11:21 AM , Rating: 2
taxicab!? try a asian's house!
SENSORY OVERLOAD TOO MUCH CURRY!


RE: o.0
By ggordonliddy on 10/1/2008 6:03:29 PM , Rating: 2
quote:
a asian's house!


It's " an Asian's house!" Now you have learned.


RE: o.0
By Trisagion on 10/1/2008 8:14:46 AM , Rating: 2
You could probably just switch off your nose with a thought.


RE: o.0
By DeepBlue1975 on 10/1/2008 8:35:24 AM , Rating: 3
No, it wouldn't work like that.
You should telnet port 400 of 192.168.0.1 from a terminal interfaced via your left year (you could use bluetooth earpieces for a wireless interface using a PAN), type "hypernose_dis -a -s -t /e:2", and then logoff.


RE: o.0
By Gzus666 on 10/1/2008 8:49:42 AM , Rating: 5
Wouldn't you rather SSH in? Don't want someone "sniffing" your unencrypted traffic, then breaking into your nosenet.


RE: o.0
By rudolphna on 10/1/2008 11:12:31 AM , Rating: 2
*chuckles* Puns as far as the eye can see.... or your remotely operated nose can smell


RE: o.0
By snownpaint on 10/1/2008 5:54:59 PM , Rating: 2
you could VPN into someone else nosenet, to see if the milk really does smell bad.


RE: o.0
By DeepBlue1975 on 10/2/2008 10:03:31 AM , Rating: 2
You are completely right!!!

But if I were you, I wouldn't give much thought to security. I'm pretty sure that some public "nose hosts" will offer free accounts to users who wanna keep a live feed of what they smell so everybody can sniff their webs.

Example
Alix3_TheBlueLatexKid16_1992 posts: "hell-o pee paul, hear I am in the badroom dooing #2, after I 8 zome stroguhverry kake. Don't my sheet smell wood? Post yer komments!"

You should also be able to program your nose to permanently feel some kind of perfume to avoid unpleasant smells :D


Waterlogged
By ggordonliddy on 10/1/2008 6:04:53 PM , Rating: 2
quote:
To compound this, olfactory proteins are remarkably difficult to study outside of the body as their composition makes them hydrophobic and causes them to lose their structure in water-based solutions.


This is why you cannot smell underwater, and why skin divers and goldfish permanently lose their sense of smell.




RE: Waterlogged
By Tegeril on 10/1/2008 7:25:10 PM , Rating: 3
Last I checked, I couldn't smell underwater because I couldn't breathe underwater...


RE: Waterlogged
By ggordonliddy on 10/1/2008 11:17:25 PM , Rating: 4
Wrong. You aren't trying hard enough.


RE: Waterlogged
By Cincybeck on 10/2/2008 7:12:40 PM , Rating: 2
+1 I chuckled out loud. I'll admit it. Makes me wonder though if these proteins are hydrophobic how do Catfish smell? They have two olfactory pits on their head with four holes. Two intakes, two exhaust. They can smell something that is only 1 part to 10 billion parts water.


Somewhere out there today...
By IceBreakerG on 10/1/2008 8:54:54 AM , Rating: 2
Michael Jackson is singing a happy song and calling his doctor to put him at the top of the waiting list. Hee hee!




RE: Somewhere out there today...
By FITCamaro on 10/1/2008 12:15:55 PM , Rating: 2
And a child is sitting in his closet naked weeping.


they shoulda named it...
By jlips6 on 10/1/2008 6:33:23 PM , Rating: 2
"Breaking the Smell Barrier"




"Nowadays, security guys break the Mac every single day. Every single day, they come out with a total exploit, your machine can be taken over totally. I dare anybody to do that once a month on the Windows machine." -- Bill Gates











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