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Dr. Antonio Amodeo  (Source: EPA)
The 10 hour operation has given him 20-25 additional years of life

A 15-year-old boy from Italy is now the first child patient ever to receive a permanently implanted artificial heart. The boy, who remains unnamed for now, has been dealing with an illness called Duchenne syndrome, which causes rapid muscle degeneration. He was close to death and confined to a bed with no ability to walk, and was still ineligible to be added to a waiting list for a heart transplant. 

This is when Dr. Antonio Amodeo, a pediatric cardiac surgeon, decided to perform a heart transplant on the boy. But unlike previous artificial heart transplant's, this would not just be a temporary fix. This operation would serve as a permanent solution in hopes of giving the boy a "normal life." The procedure was also unlike any other artificial heart operation because this was the first time it was performed on a child. 

"The device is an electronically activated hydraulic pump and is entirely located inside the thorax, in order to reduce the risk of infection," said Dr. Amodeo. "It is powered through a plug positioned behind the left ear and connected to the battery that the patient holds on a belt and is charged during the night like a mobile phone."

The artificial heart is approximately 4cm long and weighs about 14 ounces. After 10 hours of operating last week, the boy is still in intensive care, but woke up after surgery and is doing fine. 

"Despite the length of the operation, he woke up fine and when his mother called, he said he could not talk as he was brushing his teeth," said Dr. Amodeo. 

The boy is expected to be in intensive care for two more weeks, and with his new artificial heart permanently implanted, he has gained another 20-25 years of life. 

"This is the first time such a device has been placed in a young child and should give him an improved quality of life even though he is suffering from Duchenne syndrome," said Dr. Amodeo. "The family was happy for the child to go through the surgery and have the artificial heart implanted as he was in a very bad way and was days away from dying.

"This surgery opens up new horizons as there are many children who need transplants, but the number of donors is very small and there are some who, like this patient, cannot be transplant candidates because of illness."



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Super cool...
By MrBlastman on 10/4/2010 9:49:15 AM , Rating: 5
This is the kind of science I love to hear about--the kind that advances our civilization. This kid was near death with no apparent cure and now, all of a sudden, he might have another twenty to twenty five years ahead of him.

I would like to see some more details though. Stuff like--what heart was used, who is the manufacturer, are the batteries using induction to transfer power to the unit, etc. These things would greatly enhance the article. I can't complain though, I enjoy seeing science tech on here, far more than reading about cell phones.

I think the next step if this heart works, is scientists somehow figuring out how to grow a new heart for someone with stem cells. In this boy's case, though, I don't think even that would have saved him given the muscular-degenerative condition he's afflicted with. So, I think we'll need both in the future, both biological and mechanical replacements.




RE: Super cool...
By Treknologist on 10/4/2010 10:08:01 AM , Rating: 2
This is definitely an significant advancement and one that can potentially help many people. I know there are people who thing that technology is a bad thing but, in truth, technology is neither good nor bad. It's how technology gets used that determines that. This is a great example of how technology is used for something good.


RE: Super cool...
By superPC on 10/4/2010 10:14:23 AM , Rating: 5
the boy would be fine as long as he stays clear of any compressed tetryon beam.


RE: Super cool...
By rika13 on 10/4/10, Rating: -1
RE: Super cool...
By Reclaimer77 on 10/4/2010 11:45:13 AM , Rating: 3
Damn you! I was going to make a Jean Luc Picard joke first! :)


RE: Super cool...
By AstroGuardian on 10/4/2010 10:21:09 AM , Rating: 2
Resistance is futile!

Jokes aside, does anyone know whether this is just an addition to the biological heart or is a total replacement? It can't be seen clearly from the attached photo...


RE: Super cool...
By nvalhalla on 10/4/2010 10:28:41 AM , Rating: 2
quote:
Dr Amodeo said the artificial heart was around 4cm long and had been placed inside the left ventricle and its connection with the ascending aorta.


From the source article.


RE: Super cool...
By Spivonious on 10/4/2010 10:37:45 AM , Rating: 3
His other muscles will still continue deteriorating until he can no longer move. It's nice that he could continue living for a while, but it will not be a "normal life".


RE: Super cool...
By skepticallizzie on 10/4/2010 1:58:54 PM , Rating: 2
Yes, that is exactly what will happen. and then when he goes into respiratory failure, they will also give him an artificial airway and put him on a vent. Then he will never die. He will be trapped in his body with an intact brain and intellect.
Yes, his life will never be "normal".
I love science, and just because we CAN do something to prolong life, it does not mean we SHOULD do it. Death is a natural part of the circle of life. We collectively tend to try to outsmart it, but in the end we all die.
(i have been a peds ICU nurse for a long time)


RE: Super cool...
By mac2j on 10/4/2010 8:32:47 PM , Rating: 3
Ugh I can't stand comments like this.

Wake up and smell the future.

Really ... you really think in 20-25 years Duchenne's won't be curable? Really?

FYI - it's already curable in animals with properly differentiated stem cells and with iPS cells. In another year he can probably get cured in China ... in another 10 he could get cured here.

This is what I often recommend to cancer patients now - do whatever you can to stay alive for a couple more years because the cures are coming.


RE: Super cool...
By Howard on 10/4/2010 8:49:46 PM , Rating: 3
So just because death is our tradition, we should never try to extend life?


RE: Super cool...
By JediJeb on 10/5/2010 2:09:59 PM , Rating: 2
quote:
He will be trapped in his body with an intact brain and intellect. Yes, his life will never be "normal".


People may think this is a horrible life, but I imagine Stephen Hawkings might have something to say about that.

Give this young person another 20-25 years and they may just be the person who finds the cure for their own illness and that of many others. Sometimes a mind can do wonderful things when it isn't encumbered by thinking about doing the things most of us call living.


RE: Super cool...
By Murloc on 10/4/2010 11:21:16 AM , Rating: 1
he will die because of his unability to breath then.
They just gave him more 20 years of shitty life.


RE: Super cool...
By dark matter on 10/4/2010 1:05:48 PM , Rating: 1
If you were given the choice, what would you do? Say fuck it, or opt for the operation.


RE: Super cool...
By ShaolinSoccer on 10/4/2010 1:44:52 PM , Rating: 3
Maybe within 20 years, there will be a cure for his disease then he can live a full "normal" life.


RE: Super cool...
By Durrr on 10/4/2010 10:03:18 PM , Rating: 3
Not only did they extend his life, but he's proven that a permanent artificial heart works! It's kind of like donating your body to science with the benefit of life.


RE: Super cool...
By JediJeb on 10/5/2010 2:16:19 PM , Rating: 1
Depends on how you define "shitty life". Maybe he has no interest at all in doing the things YOU like to do that make YOUR life great. So what if he can't play sports, go dancing, or run to a bar every night, I don't do any of those things and think my life is great, yet some people think they would die if they couldn't do those things. One person's great life is another person's hell, and vice versa.

In all of the interviews I have seen with Stephen Hawkings I have never seen him complain about his circumstances. He works hard to make the best of his life and has lived it fully. Maybe this kid will be even more brilliant than him, who knows.


power failure?
By carigis on 10/4/2010 11:12:54 AM , Rating: 2
I forget to charge my phone all the time.. would suck if he in a few years after he is used to it.. he is out traveling and caught in a power failure or just gets really drunk and forgets to charge his artificial heart..




RE: power failure?
By dark matter on 10/4/2010 1:06:54 PM , Rating: 2
You are hardly likely to "forget" something so fundamental to your existence.


RE: power failure?
By dsraa on 10/4/2010 1:12:13 PM , Rating: 2
Really?

I forget to buckle my seat belt all the time...


RE: power failure?
By Skywalker123 on 10/4/2010 1:21:57 PM , Rating: 2
Buckling your seat belt isn't fundamental to your existence no matter what the gubmint told you.


RE: power failure?
By MrBlastman on 10/4/2010 1:27:07 PM , Rating: 1
Hmm sooo what else is going to keep you in the car when you flip over multiple times in a crash? Your grip?

I can't imagine driving a car without a seatbelt on. They hold you in place so you can drive like a maniac. :)


RE: power failure?
By drumhellar on 10/4/2010 3:41:17 PM , Rating: 2
Either way, it's the crash/flipping that kills you, not the lack of seat belt.


RE: power failure?
By redbone75 on 10/4/2010 7:10:49 PM , Rating: 2
I wonder who the Darwin award candidates who voted this down are? Seat belts help save lives and are only part of ever advancing vehicle safety systems. It's that whole thing about inertia. You know, the part where your body continues at whatever speed you're driving at until something acts upon it to stop it. Would you prefer that to be the seat belt or the steering wheel? Dashboard? Windshield? That hot blond in the other vehicle you just crashed into? I don't need the government to tell me this. I learned it a looong time ago.

Look, I'm all with some people on the whole "government doesn't need to tell me how to live my life" blah blah blah kick. If, however, living your life involves putting other people at risk (and you are putting not just yourself at risk when you don't wear a seat belt) and you lack the competence to see otherwise, someone needs to tell you. I think it's sad that in many cases it ends up being government that has to be that entity in matters that involve what is basically common sense.


Gaining 20-25 years of life?
By Sylar on 10/4/2010 1:47:39 PM , Rating: 2
Curious... so what exactly happens after 20-25 years? He'll just die naturally because his body finally realizes it doesn't have a real heart? Or is it some known mechanical issue? Couldn't that be fixed somehow?




RE: Gaining 20-25 years of life?
By MrBlastman on 10/4/2010 1:54:25 PM , Rating: 2
No, his disease he is suffering from will esentially render his complete neuro-muscular system non-functional. His heart might beat, but nothing else in his body will be able to work. Sad, but, read a little about the disease. It is quite tragic. :(


RE: Gaining 20-25 years of life?
By Silver2k7 on 10/7/2010 3:29:10 PM , Rating: 2
But who knows his condition might be curable before it comes to that.. 20-25 years is a long time, especially in these days whith stemcells and nanotech wich are both new fields that will see lots of research in two decades.


JUST like this
By ninus3d on 10/4/2010 8:42:36 PM , Rating: 4
Stories JUST like this is why I slave 16 hours a day, 7 days a week with school and homework to get into medical science.
The sheer RUSH of having been a part, regardless of how small, to help someone in need like this, I LOVE the possibilities that exists today!




Sounds like a VAD
By kaborka on 10/4/2010 4:51:53 PM , Rating: 2
By chunkymonster on 10/7/2010 9:59:53 AM , Rating: 2
Just hope this kid can pay the medical bills lest the Repo Men from The Union come and cut it out of him.

In all seriousness, this is encouraging news and an exciting development. Hope this kid lives many years and the technology continues to improve.




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