Remote Control Cancer Killers
November 20, 2007 9:12 AM
comment(s) - last by
Sticky nanoparticles find tumor cells where they can be used to release drugs straight to the culprit
Building on past research with sticky nanoparticles, scientists at MIT have developed a method of delivering drugs straight to tumor cells. Previously the particles, which flow discretely through the bloodstream adhering only to tumorous cells, helped visualize tumors via magnetic resonance imaging. Now, using electromagnetic wave pulses, the same particles could be used to bomb the tumor cells with drugs.
The researches found that they could use the superparamagnetic properties of certain nanoparticles to activate, or in this case destroy, bonds holding drug molecules to the particles. Superparamagenetic materials have the property of giving off heat when exposed to a magnetic field.
The researchers used low-frequency wave pulses with frequencies between 350 and 400 kilohertz. These frequencies are much lower than much-feared microwaves, and pass harmlessly through the body, affecting only the nanoparticle delivery vehicles.
The microscopic drug tethers are made from strands of DNA. What makes the DNA molecule a good choice is that it can be created to melt with different amounts of heat based on strand lengths and coding. This could allow each particle to have several kinds of drug molecules attached to it, thus safely customizing treatment by simply modulated the pulse's frequency.
Though tests in the lab involving mice and implanted faux-tumors saturated with the drug bomb nanoparticles have been successful, the team of researchers is still doing work to guarantee that enough of the drug-ferrying particles will clump together inside of a tumor naturally to be effective.
"Our overall goal is to create multi-functional nanoparticles that home to a tumor, accumulate, and provide customizable remotely activated drug delivery right at the site of the disease," said Sangeeta Bhatia, M.D., Ph.D, an associate professor at the Harvard-MIT Division of Health Science and Technology and MIT's Department of Electrical Engineering and Computer Science.
This article is over a month old, voting and posting comments is disabled
11/20/2007 9:04:18 PM
Actually I heard recently they had a gene that could be spliced to your own DNA and re-injected into your body. Then the gene would reproduce and erradicate the cancer. One of my customers is good friends with some people at John Hopkins. It's really interesting what they are up to over there.
"When an individual makes a copy of a song for himself, I suppose we can say he stole a song." -- Sony BMG attorney Jennifer Pariser
Temple University Researchers Hit the Delete Button on HIV, Remove it from Human Cells
July 22, 2014, 7:39 AM
Airbus Shows Off All-Electric E-Fan 2.0 Airplane, Plans Production in 2017
July 21, 2014, 9:29 AM
Buzz Aldrin Says First Astronauts to Set Foot on Mars Should Never Return Home
July 9, 2014, 9:46 AM
Women May Soon Be Able to Control Their Fertility via Remote Control
July 7, 2014, 10:14 AM
Tiny "Bio-bots" Powered by Muscle Cells, Electrical Pulses
July 3, 2014, 7:00 PM
Boston Using Solar-Powered Benches as Phone Charging Stations
July 1, 2014, 1:09 PM
Most Popular Articles
Microsoft Kills Entertainment Unit, May Shelve Flagship Lumia "McLaren"
July 18, 2014, 7:40 PM
Boeing 777 Malaysian Airlines Flight 17 Crashes in Ukraine
July 17, 2014, 1:00 PM
Google Signs Controversial Deal With Pharmaceutical Giant Novartis
July 16, 2014, 7:32 PM
Toyota Scientist: Autonomous Vehicles May Lead to Increased Fuel Consumption, Pollution
July 18, 2014, 2:42 PM
JJ Abrams Unveils X-Wing Starfighter for New "Star Wars" Movie
July 21, 2014, 12:24 PM
Latest Blog Posts
Space Terrorism is a Looming Threat For the United States
Apr 23, 2014, 7:47 PM
Facebook Aims to Provide Internet to "Every Person in the World" with Drones, Satellites
Apr 1, 2014, 10:20 AM
Retail Mobile Sites Experience Outages in Light of Simplexity's Bankruptcy
Mar 14, 2014, 8:48 AM
Tesla vs. BMW: Who Has the Safer EV?
Feb 1, 2014, 2:56 PM
Justice Leaks Details of Next HTC One Two Flagship Phone
Dec 5, 2013, 4:04 PM
More Blog Posts
Copyright 2014 DailyTech LLC. -
Terms, Conditions & Privacy Information