Sources: Gladstone Insitutes, Stem Cell Reports [Press Release]
quote: Researchers are describes that the human body is much more strange and pliable than previously thought
quote: Dr. Srivastava first discovered that a cocktail of three genes injected into mice could provoke fibroblast cells to become cardiomyocytes -- the cells that pump blood in a beat heart.
quote: While the holy grail of tissue engineer has long thought to have been to develop fully pluripotent, sustainable stem cell colonies and then trigger them to differentiate into desired cells of any kind, that has proven tricky in practice.
quote: Complex tissue parameters -- pressure, local nutrients, and signals from surrounding cells -- have all be found to influence what target a stem cell decides to become, making what seemed an easy route far harder.
quote: So some researchers like Dr. Srivastava have turned in part to look into ways to trick local cell types near a damaged tissue into becoming the type of cells in the damaged tissue via gene theory.