Urine Provides Stem Cells Capable of Multiple Therapies
August 1, 2013 3:15 PM
comment(s) - last by
Stem cells can be isolated from urine and transformed into multiple cell types without the use of expensive and invasive surgeries
Scientists have found a way to harvest stem cells -- which are capable of becoming many types of cells for different therapies --
easily from urine
Researchers from Wake Forest Baptist Medical Center's Institute for Regenerative Medicine -- led by Yuanyuan Zhang, M.D., Ph.D., assistant professor of regenerative medicine -- have found that stem cells can be isolated from urine and transformed into multiple cell types without the use of expensive and invasive surgeries.
Isolating stem cells from organs and tissues can be difficult because it's a very small population of cells. Also, taking the stem cells from urine means transforming into many cell types instead of just one.
The research team originally found the cells in urine back in 2006. They discovered that these cells don't form tumors when implanted in the body like iPS cells or embryonic stem cells, making them great candidates for patient use.
Also, using stem cells from the patient's body is a good idea because there's no worry of immune rejection.
The team took urine samples from 17 healthy individuals ranging from ages five to 75. They then processed it and looked at the cells' ability to turn into multiple types.
From there, the cells differentiated into the three tissue layers -- endoderm, ectoderm and mesoderm -- and directed them to become bladder-type cells, such as smooth muscle and urothelial. These cells line the bladder.
The cells were placed in scaffolds made of pig intestine, and when they were
implanted in mice
for one month, the cells formed tissue-like structures with multiple layers.
The stem cells also had the ability to become other types, such as mesenchymal cells, which are adult stem cells from connective tissue like bone marrow. They also showed markers for pericytes, which are a subset of mesenchymal cells located in small blood vessels.
"These stem cells represent virtually a limitless supply of autologous cells for treating not only urology-related conditions such as kidney disease, urinary incontinence and erectile dysfunction, but could be used in other fields as well," said Zhang. "They could also potentially be used to engineer replacement bladders, urine tubes and other urologic organs."
This article is over a month old, voting and posting comments is disabled
working in home
8/3/2013 3:42:54 AM
my neighbor's aunt makes $73/hour on the computer. She has been fired for eight months but last month her payment was $15845 just working on the computer for a few hours. Read more here www.work25.Com
"My sex life is pretty good" -- Steve Jobs' random musings during the 2010 D8 conference
Mice Receive Human Embryonic Stem Cells to Treat Damaged Brain
April 22, 2013, 5:22 PM
Chinese Scientists Produce Neurons from Urine
December 11, 2012, 11:29 PM
Quick Note: Drone Loses Fight to the Death With Kangaroo
December 23, 2014, 3:28 PM
Campbell's Monkeys Found to Use Different Dialects to Describe Local Threats
December 22, 2014, 3:52 PM
Scientist Confirm Men are More Likely to Die in "Idiotic" Ways
December 17, 2014, 1:07 PM
Shoppers Surprised to Find Cards Against Humanity's Bullsh*t is Real Feces
December 16, 2014, 11:14 PM
Air Force Worries Hot Fuel Could Harm F-35, "Proactively" Paints Trucks Shiny
December 11, 2014, 9:06 AM
McDonald's is Testing Tablet-Based Burger Customization at 30 Franchises
December 10, 2014, 11:30 AM
Most Popular Articles
Miyamoto: Nintendo is Prepping Successor to Troubled Wii U
December 22, 2014, 6:28 PM
Amazon's Kindle Fire HDX 8.9 Drops to $299 (30 Percent Off) for a Day
December 22, 2014, 10:57 AM
Airbus A350 XWB Passenger Jet Takes Off, First Unit Delivered to Qatar Airlines
December 22, 2014, 1:22 PM
Microsoft, Google Back The Interview, North Korea Vows Attacks on America
December 24, 2014, 4:25 PM
Nokia's Sweet $250 Android Lollipop N1 Tablet is Rumored for Jan. 7 China Launch
December 24, 2014, 1:45 PM
Latest Blog Posts
Sceptre Airs 27", 120 Hz. 1080p Monitor/HDTV w/ 5 ms Response Time for $220
Dec 3, 2014, 10:32 PM
Costco Gives Employees Thanksgiving Off; Wal-Mart Leads "Black Thursday" Charge
Oct 29, 2014, 9:57 PM
"Bear Selfies" Fad Could Turn Deadly, Warn Nevada Wildlife Officials
Oct 28, 2014, 12:00 PM
The Surface Mini That Was Never Released Gets "Hands On" Treatment
Sep 26, 2014, 8:22 AM
ISIS Imposes Ban on Teaching Evolution in Iraq
Sep 17, 2014, 5:22 PM
More Blog Posts
Copyright 2014 DailyTech LLC. -
Terms, Conditions & Privacy Information