Urine Provides Stem Cells Capable of Multiple Therapies
August 1, 2013 3:15 PM
comment(s) - last by
Stem cells can be isolated from urine and transformed into multiple cell types without the use of expensive and invasive surgeries
Scientists have found a way to harvest stem cells -- which are capable of becoming many types of cells for different therapies --
easily from urine
Researchers from Wake Forest Baptist Medical Center's Institute for Regenerative Medicine -- led by Yuanyuan Zhang, M.D., Ph.D., assistant professor of regenerative medicine -- have found that stem cells can be isolated from urine and transformed into multiple cell types without the use of expensive and invasive surgeries.
Isolating stem cells from organs and tissues can be difficult because it's a very small population of cells. Also, taking the stem cells from urine means transforming into many cell types instead of just one.
The research team originally found the cells in urine back in 2006. They discovered that these cells don't form tumors when implanted in the body like iPS cells or embryonic stem cells, making them great candidates for patient use.
Also, using stem cells from the patient's body is a good idea because there's no worry of immune rejection.
The team took urine samples from 17 healthy individuals ranging from ages five to 75. They then processed it and looked at the cells' ability to turn into multiple types.
From there, the cells differentiated into the three tissue layers -- endoderm, ectoderm and mesoderm -- and directed them to become bladder-type cells, such as smooth muscle and urothelial. These cells line the bladder.
The cells were placed in scaffolds made of pig intestine, and when they were
implanted in mice
for one month, the cells formed tissue-like structures with multiple layers.
The stem cells also had the ability to become other types, such as mesenchymal cells, which are adult stem cells from connective tissue like bone marrow. They also showed markers for pericytes, which are a subset of mesenchymal cells located in small blood vessels.
"These stem cells represent virtually a limitless supply of autologous cells for treating not only urology-related conditions such as kidney disease, urinary incontinence and erectile dysfunction, but could be used in other fields as well," said Zhang. "They could also potentially be used to engineer replacement bladders, urine tubes and other urologic organs."
This article is over a month old, voting and posting comments is disabled
working in home
8/3/2013 3:40:12 AM
If you think Edwin`s story is terrific,, 2 weeks ago mother in law also made $7561 sitting there 20 hour's a week at home and their buddy's mother-in-law`s neighbour has been doing this for 9-months and earnt more than $7561 parttime on their labtop. use the guide from this site,
RE: working in home
8/3/2013 3:43:17 AM
"If you can find a PS3 anywhere in North America that's been on shelves for more than five minutes, I'll give you 1,200 bucks for it." -- SCEA President Jack Tretton
Mice Receive Human Embryonic Stem Cells to Treat Damaged Brain
April 22, 2013, 5:22 PM
Chinese Scientists Produce Neurons from Urine
December 11, 2012, 11:29 PM
Nail Polish May Soon be Able to Detect Date Rape Drugs
August 26, 2014, 7:57 AM
SpaceX Falcon 9-R Rocket Suffers Malfunction, Self-Destructs During Test Flight
August 23, 2014, 9:36 AM
Texas Chosen as Site for SpaceX's First Commercial Launchpad
August 5, 2014, 1:44 PM
South Carolina Prison Finds Crashed Drone Carrying Drugs, Phones
August 1, 2014, 2:49 PM
NASA's Mars 2020 Rover Gains Seven New Instruments for Exploration
August 1, 2014, 1:30 PM
NASA Opportunity Rover Breaks Record for Most Miles Traveled on Another Planet
July 29, 2014, 1:38 PM
Most Popular Articles
Apple Announces 4.7" iPhone 6, 5.5" iPhone 6 Plus
September 9, 2014, 1:45 PM
Apple Announces Its Smartwatch: The $349 Apple Watch
September 9, 2014, 2:09 PM
Appalling Negligence: Decade-Old Windows XPe Holes Led to Home Depot Hack
September 8, 2014, 8:58 PM
T-Mobile Launches Un-carrier 7.0, Beefs Up Wi-Fi Calling
September 11, 2014, 2:56 PM
HTC Preps Nexus 9 With Nvidia K1 64-Bit "Denver" SoC, Android L Onboard
September 10, 2014, 10:21 PM
Latest Blog Posts
Space Terrorism is a Looming Threat For the United States
Apr 23, 2014, 7:47 PM
Facebook Aims to Provide Internet to "Every Person in the World" with Drones, Satellites
Apr 1, 2014, 10:20 AM
Retail Mobile Sites Experience Outages in Light of Simplexity's Bankruptcy
Mar 14, 2014, 8:48 AM
Tesla vs. BMW: Who Has the Safer EV?
Feb 1, 2014, 2:56 PM
Justice Leaks Details of Next HTC One Two Flagship Phone
Dec 5, 2013, 4:04 PM
More Blog Posts
Copyright 2014 DailyTech LLC. -
Terms, Conditions & Privacy Information