Urine Provides Stem Cells Capable of Multiple Therapies
August 1, 2013 3:15 PM
comment(s) - last by
Stem cells can be isolated from urine and transformed into multiple cell types without the use of expensive and invasive surgeries
Scientists have found a way to harvest stem cells -- which are capable of becoming many types of cells for different therapies --
easily from urine
Researchers from Wake Forest Baptist Medical Center's Institute for Regenerative Medicine -- led by Yuanyuan Zhang, M.D., Ph.D., assistant professor of regenerative medicine -- have found that stem cells can be isolated from urine and transformed into multiple cell types without the use of expensive and invasive surgeries.
Isolating stem cells from organs and tissues can be difficult because it's a very small population of cells. Also, taking the stem cells from urine means transforming into many cell types instead of just one.
The research team originally found the cells in urine back in 2006. They discovered that these cells don't form tumors when implanted in the body like iPS cells or embryonic stem cells, making them great candidates for patient use.
Also, using stem cells from the patient's body is a good idea because there's no worry of immune rejection.
The team took urine samples from 17 healthy individuals ranging from ages five to 75. They then processed it and looked at the cells' ability to turn into multiple types.
From there, the cells differentiated into the three tissue layers -- endoderm, ectoderm and mesoderm -- and directed them to become bladder-type cells, such as smooth muscle and urothelial. These cells line the bladder.
The cells were placed in scaffolds made of pig intestine, and when they were
implanted in mice
for one month, the cells formed tissue-like structures with multiple layers.
The stem cells also had the ability to become other types, such as mesenchymal cells, which are adult stem cells from connective tissue like bone marrow. They also showed markers for pericytes, which are a subset of mesenchymal cells located in small blood vessels.
"These stem cells represent virtually a limitless supply of autologous cells for treating not only urology-related conditions such as kidney disease, urinary incontinence and erectile dysfunction, but could be used in other fields as well," said Zhang. "They could also potentially be used to engineer replacement bladders, urine tubes and other urologic organs."
This article is over a month old, voting and posting comments is disabled
working in home
8/3/2013 3:40:12 AM
If you think Edwin`s story is terrific,, 2 weeks ago mother in law also made $7561 sitting there 20 hour's a week at home and their buddy's mother-in-law`s neighbour has been doing this for 9-months and earnt more than $7561 parttime on their labtop. use the guide from this site,
RE: working in home
8/3/2013 3:43:17 AM
"The whole principle [of censorship] is wrong. It's like demanding that grown men live on skim milk because the baby can't have steak." -- Robert Heinlein
Mice Receive Human Embryonic Stem Cells to Treat Damaged Brain
April 22, 2013, 5:22 PM
Chinese Scientists Produce Neurons from Urine
December 11, 2012, 11:29 PM
Creationists are Mad About Google Doodle Depicting Evolution
November 24, 2015, 8:48 PM
DHS and TSA: Whoops, We Missed That 73 Airport Employees May be Terrorists
November 19, 2015, 2:16 PM
Star Wars Spinoff Film "Rogue One", Theme Park Attractions Announced
August 17, 2015, 12:20 PM
SpaceX Falcon 9's Seventh Supply Mission to ISS Ends w/ Fiery Stage 1 Explosion
June 28, 2015, 1:10 PM
Cool Science Video: Glowing Millipede Prowls the Nevada Desert
May 18, 2015, 12:00 PM
Newly Discovered Costa Rican Glass Frog is Kermit's Doppelgänger
April 22, 2015, 11:26 AM
Latest Blog Posts
Sceptre Airs 27", 120 Hz. 1080p Monitor/HDTV w/ 5 ms Response Time for $220
Dec 3, 2014, 10:32 PM
Costco Gives Employees Thanksgiving Off; Wal-Mart Leads "Black Thursday" Charge
Oct 29, 2014, 9:57 PM
"Bear Selfies" Fad Could Turn Deadly, Warn Nevada Wildlife Officials
Oct 28, 2014, 12:00 PM
The Surface Mini That Was Never Released Gets "Hands On" Treatment
Sep 26, 2014, 8:22 AM
ISIS Imposes Ban on Teaching Evolution in Iraq
Sep 17, 2014, 5:22 PM
More Blog Posts
Copyright 2016 DailyTech LLC. -
Terms, Conditions & Privacy Information