New Blood Test May One Day Act as Alternative to Colonoscopy for Cancer Detection
June 7, 2013 12:05 PM
comment(s) - last by
The blood test looks for changes in one particular gene called SDC2
Researchers in South Korea have found an alternative to a colonoscopy for detecting colon cancer.
The study, conducted by researchers from Genomictree Inc. and Yonsei University College of Medicine in Seoul, offers a noninvasive and simple blood test for colon cancer.
The blood test watches the methylation of genes, which is a biochemical process vital to how genes function are expressed. By looking at this process, researchers can pinpoint a set of genes with methylation patterns that are found in tissues from colon cancer tumors.
The researchers look for changes in
one particular gene
called SDC2, which is linked to colon cancer growth.
To see if the new blood test worked, the research team took tissues from 133 colon cancer patients and tissues from healthy patients as well.
Using the gene-based screen test, accurate detection of stage 1 cancer occurred 92 percent of the time. For later stages of cancer, accurate detection dropped to 87 percent.
For those without cancer, the blood test detected so 95 percent of the time.
According to lead study author TaeJeong Oh, these results indicate "SDC2 is suitable for early detection of [colorectal cancer] where therapeutic interventions have the greatest likelihood of curing the patient from the disease."
This blood test could give patients
a simple alternative
to colon cancer detection instead of the invasive colonoscopy. As far as accuracy goes, the blood test is in its early stages and will need more studies by others in order to progress.
Today's stool tests can't detect cancer every time, and the colonoscopy isn't 100 percent every time either. A colonoscopy can miss polyps because they are hidden in the crevices of the intestines.
With more research, the simple blood test could one day be an easier and more accurate method of detection.
This article is over a month old, voting and posting comments is disabled
6/7/2013 3:40:16 PM
While sensational (and certainly bad), these events are exceedingly rare. What's more common are complications - having operated on numerous colonoscopy related issues (perforation of the colon), it's not a procedure without risk.
Ultimately I think the best part of this is that it's not operator-dependent like a colonoscopy is (i.e. how good is your endoscopist). People quote upwards of 95% sensitivity for colonoscopy but that's in large academic centers - outside the ivory tower who knows.
"Death Is Very Likely The Single Best Invention Of Life" -- Steve Jobs
Peptide-Coated Nanoparticles Offer Early Cancer Detection in Urine
December 19, 2012, 8:35 AM
New Rogue Gene Offers Insight on How to Stop Cancer from Spreading
January 24, 2011, 9:04 AM
Creationists are Mad About Google Doodle Depicting Evolution
November 24, 2015, 8:48 PM
DHS and TSA: Whoops, We Missed That 73 Airport Employees May be Terrorists
November 19, 2015, 2:16 PM
Star Wars Spinoff Film "Rogue One", Theme Park Attractions Announced
August 17, 2015, 12:20 PM
SpaceX Falcon 9's Seventh Supply Mission to ISS Ends w/ Fiery Stage 1 Explosion
June 28, 2015, 1:10 PM
Cool Science Video: Glowing Millipede Prowls the Nevada Desert
May 18, 2015, 12:00 PM
Newly Discovered Costa Rican Glass Frog is Kermit's Doppelgänger
April 22, 2015, 11:26 AM
Most Popular Articles
Free Windows 10 offer ends July 29th, 2016: 10 Reasons to Upgrade Immediately
July 22, 2016, 9:19 PM
Top 5 Smart Watches
July 21, 2016, 11:48 PM
2017 Porsche Panamera: I’ll Take Three of These.
July 24, 2016, 6:44 PM
Latest Blog Posts
Sceptre Airs 27", 120 Hz. 1080p Monitor/HDTV w/ 5 ms Response Time for $220
Dec 3, 2014, 10:32 PM
Costco Gives Employees Thanksgiving Off; Wal-Mart Leads "Black Thursday" Charge
Oct 29, 2014, 9:57 PM
"Bear Selfies" Fad Could Turn Deadly, Warn Nevada Wildlife Officials
Oct 28, 2014, 12:00 PM
The Surface Mini That Was Never Released Gets "Hands On" Treatment
Sep 26, 2014, 8:22 AM
ISIS Imposes Ban on Teaching Evolution in Iraq
Sep 17, 2014, 5:22 PM
More Blog Posts
Copyright 2016 DailyTech LLC. -
Terms, Conditions & Privacy Information