New Blood Test May One Day Act as Alternative to Colonoscopy for Cancer Detection
June 7, 2013 12:05 PM
comment(s) - last by
The blood test looks for changes in one particular gene called SDC2
Researchers in South Korea have found an alternative to a colonoscopy for detecting colon cancer.
The study, conducted by researchers from Genomictree Inc. and Yonsei University College of Medicine in Seoul, offers a noninvasive and simple blood test for colon cancer.
The blood test watches the methylation of genes, which is a biochemical process vital to how genes function are expressed. By looking at this process, researchers can pinpoint a set of genes with methylation patterns that are found in tissues from colon cancer tumors.
The researchers look for changes in
one particular gene
called SDC2, which is linked to colon cancer growth.
To see if the new blood test worked, the research team took tissues from 133 colon cancer patients and tissues from healthy patients as well.
Using the gene-based screen test, accurate detection of stage 1 cancer occurred 92 percent of the time. For later stages of cancer, accurate detection dropped to 87 percent.
For those without cancer, the blood test detected so 95 percent of the time.
According to lead study author TaeJeong Oh, these results indicate "SDC2 is suitable for early detection of [colorectal cancer] where therapeutic interventions have the greatest likelihood of curing the patient from the disease."
This blood test could give patients
a simple alternative
to colon cancer detection instead of the invasive colonoscopy. As far as accuracy goes, the blood test is in its early stages and will need more studies by others in order to progress.
Today's stool tests can't detect cancer every time, and the colonoscopy isn't 100 percent every time either. A colonoscopy can miss polyps because they are hidden in the crevices of the intestines.
With more research, the simple blood test could one day be an easier and more accurate method of detection.
This article is over a month old, voting and posting comments is disabled
Ideally blood test would screen for colonoscopy
6/7/2013 3:19:22 PM
As someone who has had the "periscope up the butt", I can attest that they knock you out before the colonoscopy, so the most uncomfortable parts are the evening before when you have to flush out your bowels with laxatives and enemas, and afterwards when trying to fart out all that air they pumped into your intestine so as to minimize those crevices where a tumor could be hiding. However both of those are definitely uncomfortable experiences.
So a simple and accurate blood test would be much preferred - only a positive test would result in a colonoscopy, during which they can snip out the suspect part and then analyze it further.
"I'm an Internet expert too. It's all right to wire the industrial zone only, but there are many problems if other regions of the North are wired." -- North Korean Supreme Commander Kim Jong-il
Peptide-Coated Nanoparticles Offer Early Cancer Detection in Urine
December 19, 2012, 8:35 AM
New Rogue Gene Offers Insight on How to Stop Cancer from Spreading
January 24, 2011, 9:04 AM
SpaceX Falcon 9-R Rocket Suffers Malfunction, Self-Destructs During Test Flight
August 23, 2014, 9:36 AM
Texas Chosen as Site for SpaceX's First Commercial Launchpad
August 5, 2014, 1:44 PM
South Carolina Prison Finds Crashed Drone Carrying Drugs, Phones
August 1, 2014, 2:49 PM
NASA's Mars 2020 Rover Gains Seven New Instruments for Exploration
August 1, 2014, 1:30 PM
NASA Opportunity Rover Breaks Record for Most Miles Traveled on Another Planet
July 29, 2014, 1:38 PM
Commercial Drones to Get Privacy Guidelines Via Executive Order
July 25, 2014, 5:34 PM
Most Popular Articles
Apple Scores Patents, Preps New Reversible USB Plug for iPhone 6 Connector
August 18, 2014, 1:32 PM
New AMD Fusion-Based Laptop From HP to Pack a Punch at $199
August 18, 2014, 4:13 PM
BlackBerry Reinvents Itself, Prepares for Potential Smartphone-Free Future
August 18, 2014, 7:51 PM
New Photos Show “Assembled” iPhone 6, Protruding Camera Ring
August 20, 2014, 2:32 PM
Lumia 830 Gets Major Upgrades Including New 20.1 Megapixel Toshiba Sensor
August 15, 2014, 6:00 PM
Latest Blog Posts
Space Terrorism is a Looming Threat For the United States
Apr 23, 2014, 7:47 PM
Facebook Aims to Provide Internet to "Every Person in the World" with Drones, Satellites
Apr 1, 2014, 10:20 AM
Retail Mobile Sites Experience Outages in Light of Simplexity's Bankruptcy
Mar 14, 2014, 8:48 AM
Tesla vs. BMW: Who Has the Safer EV?
Feb 1, 2014, 2:56 PM
Justice Leaks Details of Next HTC One Two Flagship Phone
Dec 5, 2013, 4:04 PM
More Blog Posts
Copyright 2014 DailyTech LLC. -
Terms, Conditions & Privacy Information