Rats Receive Lab-Grown Kidneys
April 16, 2013 2:08 PM
comment(s) - last by
They're not perfect, but they're a start
Researchers from Massachusetts General Hospital have transplanted lab-grown kidneys into rats, which could one day fill the need for donor organs.
Harald Ott, an organ regeneration specialist, led the Massachusetts General Hospital team.
As of right now, patients with severe kidney disease require dialysis, which acts as an artificial
by removing waste and excess water from the blood. They need this in order to live, but they could be cured with a donor kidney transplant. The problem is that around 100,000 people in the U.S. alone are waiting for that donor. There is also the possibility of the body rejecting the donor organ.
But now, Ott and his team have used rat models to transplant lab-grown kidneys that could one day
Ott first took the kidneys of recently deceased rats and stripped the cells away using detergent. He then placed two cell types in the remaining scaffold that regenerated the kidneys. These cells were kidney cells from newborn rats to produce the necessary organ tissues, and human umbilical-vein cells to line the blood vessels.
The kidneys worked, but they're not perfect yet. Once they were transplanted into the rats, they produced only around one-third as much urine as normal kidneys. They also eliminated creatinine 36 times slower than normal.
However, with time and additional research, lab-grown kidneys could be scaled up to create those suitable for humans. The researchers suspect that the lab-grown kidneys require more cell types found in real human kidneys in order to function properly.
While this method may be far from clinical use, it could one day serve those who are awaiting kidney transplants and eliminate the need for dialysis.
This article is over a month old, voting and posting comments is disabled
RE: Great news
4/17/2013 1:07:44 PM
Gov funding & gov scientists/docs/professors also invented/developed Antibiotics, X-rays, human insulin, antiseptic procedures & MRI machines as well as the internet
as well as artificial kidneys
"A lot of people pay zero for the cellphone ... That's what it's worth." -- Apple Chief Operating Officer Timothy Cook
Chinese Boy Sells One of His Kidneys For iPad 2
June 2, 2011, 12:12 PM
UCLA Researchers Design Wearable Kidney
July 16, 2008, 4:12 AM
Temple University Researchers Hit the Delete Button on HIV, Remove it from Human Cells
July 22, 2014, 7:39 AM
Airbus Shows Off All-Electric E-Fan 2.0 Airplane, Plans Production in 2017
July 21, 2014, 9:29 AM
Buzz Aldrin Says First Astronauts to Set Foot on Mars Should Never Return Home
July 9, 2014, 9:46 AM
Women May Soon Be Able to Control Their Fertility via Remote Control
July 7, 2014, 10:14 AM
Tiny "Bio-bots" Powered by Muscle Cells, Electrical Pulses
July 3, 2014, 7:00 PM
Boston Using Solar-Powered Benches as Phone Charging Stations
July 1, 2014, 1:09 PM
Most Popular Articles
Microsoft Kills Entertainment Unit, May Shelve Flagship Lumia "McLaren"
July 18, 2014, 7:40 PM
JJ Abrams Unveils X-Wing Starfighter for New "Star Wars" Movie
July 21, 2014, 12:24 PM
Boeing 777 Malaysian Airlines Flight 17 Crashes in Ukraine
July 17, 2014, 1:00 PM
Toyota Scientist: Autonomous Vehicles May Lead to Increased Fuel Consumption, Pollution
July 18, 2014, 2:42 PM
Motorola Moto G Successor Reportedly Uncovered, Moto X Discounted by up to $75
July 21, 2014, 1:11 PM
Latest Blog Posts
Space Terrorism is a Looming Threat For the United States
Apr 23, 2014, 7:47 PM
Facebook Aims to Provide Internet to "Every Person in the World" with Drones, Satellites
Apr 1, 2014, 10:20 AM
Retail Mobile Sites Experience Outages in Light of Simplexity's Bankruptcy
Mar 14, 2014, 8:48 AM
Tesla vs. BMW: Who Has the Safer EV?
Feb 1, 2014, 2:56 PM
Justice Leaks Details of Next HTC One Two Flagship Phone
Dec 5, 2013, 4:04 PM
More Blog Posts
Copyright 2014 DailyTech LLC. -
Terms, Conditions & Privacy Information