backtop


Print

They're not perfect, but they're a start

Researchers from Massachusetts General Hospital have transplanted lab-grown kidneys into rats, which could one day fill the need for donor organs.

Harald Ott, an organ regeneration specialist, led the Massachusetts General Hospital team.

As of right now, patients with severe kidney disease require dialysis, which acts as an artificial kidney replacement by removing waste and excess water from the blood. They need this in order to live, but they could be cured with a donor kidney transplant. The problem is that around 100,000 people in the U.S. alone are waiting for that donor. There is also the possibility of the body rejecting the donor organ. 

But now, Ott and his team have used rat models to transplant lab-grown kidneys that could one day benefit humans as well.

Ott first took the kidneys of recently deceased rats and stripped the cells away using detergent. He then placed two cell types in the remaining scaffold that regenerated the kidneys. These cells were kidney cells from newborn rats to produce the necessary organ tissues, and human umbilical-vein cells to line the blood vessels. 

The kidneys worked, but they're not perfect yet. Once they were transplanted into the rats, they produced only around one-third as much urine as normal kidneys. They also eliminated creatinine 36 times slower than normal.

However, with time and additional research, lab-grown kidneys could be scaled up to create those suitable for humans. The researchers suspect that the lab-grown kidneys require more cell types found in real human kidneys in order to function properly. 

While this method may be far from clinical use, it could one day serve those who are awaiting kidney transplants and eliminate the need for dialysis. 

Source: Nature





"Paying an extra $500 for a computer in this environment -- same piece of hardware -- paying $500 more to get a logo on it? I think that's a more challenging proposition for the average person than it used to be." -- Steve Ballmer
Related Articles







Latest Blog Posts
Around the World
Saimin Nidarson - Feb 18, 2017, 5:48 AM
News of Future
Saimin Nidarson - Feb 17, 2017, 6:30 AM
Some News
Saimin Nidarson - Feb 14, 2017, 5:36 AM
What's New?
Saimin Nidarson - Feb 10, 2017, 6:15 AM
Unleashed News
Saimin Nidarson - Feb 9, 2017, 6:00 AM
Eye catching news
Saimin Nidarson - Feb 8, 2017, 6:16 AM
Some World News
Saimin Nidarson - Feb 7, 2017, 6:15 AM
Today’s news
Saimin Nidarson - Feb 6, 2017, 10:11 AM
Some News
Saimin Nidarson - Feb 5, 2017, 7:27 AM
Notes and News
Saimin Nidarson - Feb 4, 2017, 5:53 AM
World News
Saimin Nidarson - Feb 3, 2017, 5:30 AM
Gadget News
Saimin Nidarson - Feb 2, 2017, 7:00 AM
News Around The World.
Saimin Nidarson - Feb 1, 2017, 7:20 AM
Some News
Saimin Nidarson - Jan 31, 2017, 7:57 AM
Tips of Today
Saimin Nidarson - Jan 30, 2017, 6:53 AM
What is new?
Saimin Nidarson - Jan 29, 2017, 6:26 AM






botimage
Copyright 2017 DailyTech LLC. - RSS Feed | Advertise | About Us | Ethics | FAQ | Terms, Conditions & Privacy Information | Kristopher Kubicki