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Print 12 comment(s) - last by PresidentThoma.. on Apr 17 at 1:07 PM

They're not perfect, but they're a start

Researchers from Massachusetts General Hospital have transplanted lab-grown kidneys into rats, which could one day fill the need for donor organs.

Harald Ott, an organ regeneration specialist, led the Massachusetts General Hospital team.

As of right now, patients with severe kidney disease require dialysis, which acts as an artificial kidney replacement by removing waste and excess water from the blood. They need this in order to live, but they could be cured with a donor kidney transplant. The problem is that around 100,000 people in the U.S. alone are waiting for that donor. There is also the possibility of the body rejecting the donor organ. 

But now, Ott and his team have used rat models to transplant lab-grown kidneys that could one day benefit humans as well.

Ott first took the kidneys of recently deceased rats and stripped the cells away using detergent. He then placed two cell types in the remaining scaffold that regenerated the kidneys. These cells were kidney cells from newborn rats to produce the necessary organ tissues, and human umbilical-vein cells to line the blood vessels. 

The kidneys worked, but they're not perfect yet. Once they were transplanted into the rats, they produced only around one-third as much urine as normal kidneys. They also eliminated creatinine 36 times slower than normal.

However, with time and additional research, lab-grown kidneys could be scaled up to create those suitable for humans. The researchers suspect that the lab-grown kidneys require more cell types found in real human kidneys in order to function properly. 

While this method may be far from clinical use, it could one day serve those who are awaiting kidney transplants and eliminate the need for dialysis. 

Source: Nature



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Great news
By BRB29 on 4/16/2013 2:24:47 PM , Rating: 2
Maybe in a decade, they can grow livers and lungs for humans in a lab. Then we can all drink and smoke all we want!




RE: Great news
By FITCamaro on 4/16/13, Rating: -1
RE: Great news
By BRB29 on 4/16/2013 3:09:59 PM , Rating: 2
someone always have to bring politics into any conversation.


RE: Great news
By Flunk on 4/16/2013 3:29:15 PM , Rating: 2
You mean Obamacare will make it possible for you to afford the operation by then. Socialized medicine actually decreases the prices of treatments. Compare prices to those of Canada, the UK or Sweden. All have much cheaper hospital care.


RE: Great news
By Kazinji on 4/16/2013 8:11:11 PM , Rating: 3
For things to be cheaper, someone has to take less. So who is going to make less? For research to go on like that someone has to fund it, where does it come from? Obamacare already adds ridiculous taxes. Companies that take care of the employee's with insurance have to play a premium tax for "Cadillac" plans, many companies are thinking of just dropping insurance altogether, silliness. Canadian's often come to US for specialist because it takes so long to so them in Canada. Seeing anything other then a general doctor forget it.


RE: Great news
By Samus on 4/16/2013 11:34:46 PM , Rating: 2
Insurance companies, that's who.


RE: Great news
By maugrimtr on 4/17/2013 9:22:26 AM , Rating: 3
quote:
Canadian's often come to US for specialist because it takes so long to so them in Canada.


That's for elective procedures, which they pay for, which means they are not public patients, which means they have private health insurance or a lot of money, which obviously means they are not stuck in a waiting list unless it for organ transplants, which means you're talking bull. Can't wait for a link to the statistics showing the extent of the non-existent Canadian hordes flooding south...


RE: Great news
By tayb on 4/17/2013 10:13:33 AM , Rating: 2
Yes, it is Obama's fault. Prior to Obamacare it was super cheap to get cured. Now, no one can afford it.

/sarcasm.

Health care in America is a embarrassment. Get cancer? Be rich, beg, or die. If only there were democratic capitalist countries out there such as Germany who managed to have solved the health care issue. Oh wait...


RE: Great news
By PresidentThomasJefferson on 4/17/2013 1:07:44 PM , Rating: 1
Gov funding & gov scientists/docs/professors also invented/developed Antibiotics, X-rays, human insulin, antiseptic procedures & MRI machines as well as the internet
as well as artificial kidneys


RE: Great news
By HostileEffect on 4/16/2013 2:52:05 PM , Rating: 2
Fully synthetic bodies will make organic replacements and gentic engineering a foot note in history. I intend to see both in my life time.


RE: Great news
By FITCamaro on 4/16/2013 3:05:15 PM , Rating: 3
You are in for a major disappointment.


RE: Great news
By dj LiTh on 4/16/2013 3:38:04 PM , Rating: 2
This is bigger news then that. Considering both lungs and liver regenerate on their own and kidney's are compartmentalized and dont regenerate much on their own.


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