Study: Early HIV Drug Treatment May Lead to Drug-Resistant Strains
March 26, 2013 10:11 AM
comment(s) - last by
Treatment in asymptomatic individuals may speed up the development of deadlier virus strains
Even as researchers creep closer to
eliminating the human immunodeficiency virus (HIV)
in some patients via intense multi-drug therapies and early treatment, researchers at the
University of Southern California
warn that the responsible treatment may give rise to new killer strains that resist drugs.
The USC study hits close to home as the Los Angeles county targets men who have sex with men (MSM) -- a high-risk group for HIV/AIDS -- with a so-called "test and treat" strategy. The strategy pushes for
-- particularly between MSM and other high-risk groups. It calls for
early retroviral drug treatment
in individuals who test HIV positive.
The approach has thus far lowered the death rates and decreased the number of cases.
The USC researchers dug into data on MSM infections, which account for 82 percent of total known HIV infections nationwide. Using data from the Centers for Disease Control, internal data, and knowledge of drug resistance, the researchers modeled the occurrence of drug resistant viral strains if the "test and treat" strategy was aggressively followed over the next several years.
The study suggests that the rates of
HIV (MDR) could jump from 4.79 percent to 9.06 percent.
Early HIV treatment may increase drug resistant viral strains.
[Image Source: Tomorrow Global]
The researchers say their results show a danger of over-treating the disease with drugs. They suggest that while the widespread testing is a good idea, that the medical establishment should back off preemptive treatment in asymptomatic individuals.
USC Professor Neeraj Sood
, who was a lead author on the study, suggests that much of the benefit comes from the knowledge of infection status. He
, "We’re not saying that testing everybody and treating everybody is bad. All we’re saying is that you should proceed with caution and closely monitor the prevalence of multi-drug-resistant HIV as you scale up the test and treat model. Prior studies show a dramatic reduction in
by individuals once they know their HIV-positive status."
The research was funded by the
Eunice Kennedy Shriver National Institute of Child Health and Human Development
in an edition of this month's
Clinical Infectious Diseases
USC [press release]
Clinical Infectious Diseases [abstract]
This article is over a month old, voting and posting comments is disabled
RE: Quicker Death or Drug Resistant HIV
3/27/2013 8:08:13 AM
Well, that worked better than I expected. This sh*t easy. I'm going to pop a champagne bottle cork now and celebrate my first troll post.
"Google fired a shot heard 'round the world, and now a second American company has answered the call to defend the rights of the Chinese people." -- Rep. Christopher H. Smith (R-N.J.)
Bill Gates: Create a Condom Men Will Use Over No Condom At All
March 25, 2013, 11:38 AM
Early HIV Treatment Rids Some Adult Patients of Pills
March 15, 2013, 1:34 PM
Baby Treated for HIV at Birth, Now A Cured Toddler
March 4, 2013, 10:41 AM
FDA Approves New "OraQuick" HIV Home Test Kit
July 5, 2012, 9:42 AM
"Superbugs" with Up to 50 Percent Drug Resistance Invade Europe
November 18, 2011, 8:54 AM
Nail Polish May Soon be Able to Detect Date Rape Drugs
August 26, 2014, 7:57 AM
SpaceX Falcon 9-R Rocket Suffers Malfunction, Self-Destructs During Test Flight
August 23, 2014, 9:36 AM
Texas Chosen as Site for SpaceX's First Commercial Launchpad
August 5, 2014, 1:44 PM
South Carolina Prison Finds Crashed Drone Carrying Drugs, Phones
August 1, 2014, 2:49 PM
NASA's Mars 2020 Rover Gains Seven New Instruments for Exploration
August 1, 2014, 1:30 PM
NASA Opportunity Rover Breaks Record for Most Miles Traveled on Another Planet
July 29, 2014, 1:38 PM
Most Popular Articles
Quick Note: Buy an Xbox One Sept 7-13, Get a Free Game
September 4, 2014, 10:42 AM
Apple Announces Its Smartwatch: The $349 Apple Watch
September 9, 2014, 2:09 PM
Dell Announces "World's Thinnest" Tablet: The Venue 8 7000 Series
September 11, 2014, 8:51 AM
Windows 9's Latest Metro Start Menu Leaks, German Site Accidentally Outs Leaker
September 11, 2014, 8:36 PM
T-Mobile Launches Un-carrier 7.0, Beefs Up Wi-Fi Calling
September 11, 2014, 2:56 PM
Latest Blog Posts
ISIS Imposes Ban on Teaching Evolution in Iraq
Sep 17, 2014, 5:22 PM
Space Terrorism is a Looming Threat For the United States
Apr 23, 2014, 7:47 PM
Facebook Aims to Provide Internet to "Every Person in the World" with Drones, Satellites
Apr 1, 2014, 10:20 AM
Retail Mobile Sites Experience Outages in Light of Simplexity's Bankruptcy
Mar 14, 2014, 8:48 AM
Tesla vs. BMW: Who Has the Safer EV?
Feb 1, 2014, 2:56 PM
More Blog Posts
Copyright 2014 DailyTech LLC. -
Terms, Conditions & Privacy Information