Study: Early HIV Drug Treatment May Lead to Drug-Resistant Strains
March 26, 2013 10:11 AM
comment(s) - last by
Treatment in asymptomatic individuals may speed up the development of deadlier virus strains
Even as researchers creep closer to
eliminating the human immunodeficiency virus (HIV)
in some patients via intense multi-drug therapies and early treatment, researchers at the
University of Southern California
warn that the responsible treatment may give rise to new killer strains that resist drugs.
The USC study hits close to home as the Los Angeles county targets men who have sex with men (MSM) -- a high-risk group for HIV/AIDS -- with a so-called "test and treat" strategy. The strategy pushes for
-- particularly between MSM and other high-risk groups. It calls for
early retroviral drug treatment
in individuals who test HIV positive.
The approach has thus far lowered the death rates and decreased the number of cases.
The USC researchers dug into data on MSM infections, which account for 82 percent of total known HIV infections nationwide. Using data from the Centers for Disease Control, internal data, and knowledge of drug resistance, the researchers modeled the occurrence of drug resistant viral strains if the "test and treat" strategy was aggressively followed over the next several years.
The study suggests that the rates of
HIV (MDR) could jump from 4.79 percent to 9.06 percent.
Early HIV treatment may increase drug resistant viral strains.
[Image Source: Tomorrow Global]
The researchers say their results show a danger of over-treating the disease with drugs. They suggest that while the widespread testing is a good idea, that the medical establishment should back off preemptive treatment in asymptomatic individuals.
USC Professor Neeraj Sood
, who was a lead author on the study, suggests that much of the benefit comes from the knowledge of infection status. He
, "We’re not saying that testing everybody and treating everybody is bad. All we’re saying is that you should proceed with caution and closely monitor the prevalence of multi-drug-resistant HIV as you scale up the test and treat model. Prior studies show a dramatic reduction in
by individuals once they know their HIV-positive status."
The research was funded by the
Eunice Kennedy Shriver National Institute of Child Health and Human Development
in an edition of this month's
Clinical Infectious Diseases
USC [press release]
Clinical Infectious Diseases [abstract]
This article is over a month old, voting and posting comments is disabled
Create Drug Resistant Strains?
3/26/2013 4:24:28 PM
They are saying that it will CREATE strains of HIV that can't be 100% cured with drugs...as in 99% of the population currently with HIV? Silly STATEMENT.
How can you create something that is already there?
"The whole principle [of censorship] is wrong. It's like demanding that grown men live on skim milk because the baby can't have steak." -- Robert Heinlein
Bill Gates: Create a Condom Men Will Use Over No Condom At All
March 25, 2013, 11:38 AM
Early HIV Treatment Rids Some Adult Patients of Pills
March 15, 2013, 1:34 PM
Baby Treated for HIV at Birth, Now A Cured Toddler
March 4, 2013, 10:41 AM
FDA Approves New "OraQuick" HIV Home Test Kit
July 5, 2012, 9:42 AM
"Superbugs" with Up to 50 Percent Drug Resistance Invade Europe
November 18, 2011, 8:54 AM
Crowdfunded Sex Toy Lets You Control the Action From Your Wii Nunchuk
January 15, 2015, 3:42 PM
Elon Musk Plays Warcraft; But Still Finds Time to Sleep, Build a Mars Colony Ship
January 6, 2015, 9:54 PM
SpaceX Scrubs Falcon 9 Launch to ISS, Barge Landing Test, Friday Redo Targeted
January 6, 2015, 4:02 PM
Quick Note; Wreckage of Malaysian-Owned Passenger Jet Found
December 30, 2014, 12:42 PM
Quick Note: Drone Loses Fight to the Death With Kangaroo
December 23, 2014, 3:28 PM
Campbell's Monkeys Found to Use Different Dialects to Describe Local Threats
December 22, 2014, 3:52 PM
Most Popular Articles
Microsoft Shows Off Latest Windows 10 Build, Preps it for Next Week Release
January 21, 2015, 2:57 PM
IDC: 2014 Sales Show PC Isn't Dead, But Desktop May be Dying
January 19, 2015, 1:50 PM
Police are Using New Handheld Radar Sensors to Peer Into Houses w/out Warrant
January 20, 2015, 1:35 PM
Great Expectations: The Rise and Fall of Google Glass Explorer Edition
January 16, 2015, 1:14 AM
Report: HTC One M9 (2015) is Tied to Under Armour-Powered HTC Smartwatch
January 19, 2015, 11:10 AM
Latest Blog Posts
Sceptre Airs 27", 120 Hz. 1080p Monitor/HDTV w/ 5 ms Response Time for $220
Dec 3, 2014, 10:32 PM
Costco Gives Employees Thanksgiving Off; Wal-Mart Leads "Black Thursday" Charge
Oct 29, 2014, 9:57 PM
"Bear Selfies" Fad Could Turn Deadly, Warn Nevada Wildlife Officials
Oct 28, 2014, 12:00 PM
The Surface Mini That Was Never Released Gets "Hands On" Treatment
Sep 26, 2014, 8:22 AM
ISIS Imposes Ban on Teaching Evolution in Iraq
Sep 17, 2014, 5:22 PM
More Blog Posts
Copyright 2015 DailyTech LLC. -
Terms, Conditions & Privacy Information