Human Embryonic Stem Cells Created with 3D Printing
February 6, 2013 2:05 PM
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Clusters of stem cells from the 3D printer
Technique could help create artificial organs
Scientists may one day be able to address organ donation shortages and the need for immunosuppressant drugs for transplants by creating artificial human organs via
A team of Heriot-Watt University scientists, led by Dr. Will Shu, has successfully used 3D printing to create clusters of embryonic stem cells -- which could, at some point, be used to produce artificial organs.
The team used an adjustable microvalve as a 3D printing technique, where layers of human
embryonic stem cells
(hESCs) were built up to create clusters of cells. HESCs are derived from early stage embryos and are capable of transforming into any tissue in the body.
"We found that the valve-based printing is gentle enough to maintain high stem cell viability, accurate enough to produce spheroids of uniform size, and most importantly, the printed hESCs maintained their pluripotency - the ability to differentiate into any other cell type," said Shu.
The technique will use cloning to create hESCs that have the patient's own genetic programming contained, meaning that the artificial organ from which the hESCs are made will not trigger a negative immune response when transplanted.
Also, this method could produce artificial human tissue for drug testing purposes.
While 3D printing of cells is nothing new, previous techniques with human stem cells have failed due to the sensitivity of these cells.
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RE: Misleading headline
2/6/2013 7:53:39 PM
Don't be silly. The majority of embryos used for this sort of thing are/were the result of IVF treatments which create many more fertilized embryos than the woman will actually need/use in order to create a statistically significant chance of at least one of them implanting successfully. The ones that don't implant/aren't needed are discarded anyways. So why not let them serve some useful purpose, since they're being created and destroyed regardless?
If and when people start getting pregnant or otherwise creating embryos *solely* with the express purpose of harvesting stem cells, then you *might* have a point. But that hasn't happened yet. And even if it had, attempting to completely block the use of embryonic stem cells would not be the way to solve that problem.
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