Artificial Pancreas Improves Glucose Control by 15%, Benefits Type 1 Diabetes Patients
January 30, 2013 5:55 PM
comment(s) - last by
Continual glucose monitor (left), pump worn on the belt that injects insulin under the patient’s skin (right), and a controller (a handheld smart phone)
(Source: Institut de recherches cliniques de Montreal)
Type 1 diabetics are expected to benefit from the new dual-hormone treatment
type 1 diabetic
is a full-time job, but a system that acts as an artificial pancreas could offer a bit of relief for those struggling to keep their glucose regulated.
An IRCM research team, led by Dr. Rémi Rabasa-Lhoret, have performed the first trial that compares an artifical pancreas system to a traditional diabetes treatment, and found that the artificial pancreas resulted in better glucose control.
The artificial pancreas is a dual-hormone system that
and glucagon automatically through the use of a continuous glucose monitor (CGM) and advanced algorithm.
The algorithm obtains data from the CGM, and it calculates the amount of insulin required. It will also calculate the required glucagon, if needed. Insulin lowers blood sugar while glucagon raises it, preventing the diabetic from experiencing hypoglycemia. Hypoglycemia is the result of blood sugar dropping too low, and can result in confusion and even loss of consciousness.
Once the insulin and glucagon is calculated, the CGM sends it to the wireless pump, and it automatically administers the proper dose of the hormones.
While pumps are available to diabetics today, the sensors must be checked frequently and the pump's dosage must be adjusted. This new system does everything without any interference from the person wearing it.
"Approximately two-thirds of patients don't achieve their target range with current treatments," said Dr. Rabasa-Lhoret. "The artificial pancreas could help them reach these targets and reduce the risk of hypoglycemia, which is feared by most patients and remains the most common adverse effect of insulin therapy. In fact, nocturnal hypoglycemia is the main barrier to reaching glycemic targets."
In the study, 15 type 1 diabetic adults that used insulin pumps for at least three months prior to the study were sent to IRCM's facility for two, 15-hour visits. During the visits, their glucose levels were monitored as they exercised on a stationary bike. They were also given an evening meal and a snack, and were sent to bed.
It turns out that the addition of glucagon and the algorithm for calculated release helped participants avoid hypoglycemia during the night. In fact, those with the dual-hormone treatment had 15 percent better glucose control than those with conventional pump treatment.
the artificial pancreas
had an 8-fold reduction in the risk of hypoglycemia, and a 20-fold reduction in the risk of hypoglycemia during the night.
This article is over a month old, voting and posting comments is disabled
RE: Become a Diabetes Warrior
2/1/2013 6:44:31 AM
Yes... I understand that but this all stems from the fact you ingest Carbohydrates. So why keep ingesting something that your body can't process?
There two other groups of energy you can ingest.
Fats and Proteins, both of which are completely viable.
RE: Become a Diabetes Warrior
2/1/2013 12:32:40 PM
It's nice of you to give a suggestion, but it wouldn't work. Type 1s need insulin whether they eat anything or not because your liver produces glucose all day long. This is the "basal" part of every T1's daily insulin regimen. And, a significant portion of fats and proteins consumed gets converted into glucose in the body, so T1's would still need insulin for food too. For example, if my T1 son ate a big hunk of cheese, his blood sugar would rise slowly but steadily for several hours without insulin. Misinformation hurts T1s because it makes people believe there's an easy fix, so why be sympathetic, fund research, provide necessary support at school, etc.
"If they're going to pirate somebody, we want it to be us rather than somebody else." -- Microsoft Business Group President Jeff Raikes
FDA Releases New Guidelines to Speed Up Artificial Pancreas Development
December 2, 2011, 1:32 PM
Researchers Use Stem Cells to Treat Diabetes in Mice
February 21, 2008, 1:05 PM
Crunch Time For Diabetes Research
June 29, 2007, 12:54 AM
SpaceX Falcon 9's Seventh Supply Mission to ISS Ends w/ Fiery Stage 1 Explosion
June 28, 2015, 1:10 PM
Cool Science Video: Glowing Millipede Prowls the Nevada Desert
May 18, 2015, 12:00 PM
Newly Discovered Costa Rican Glass Frog is Kermit's Doppelgänger
April 22, 2015, 11:26 AM
Researchers Hope to Find "Exotic" Lifeforms Inside Crater of Dinosaur Killing Meteor
April 14, 2015, 8:47 PM
Mathematician's Sociological Formulation May Explain the "Hipster Paradox"
April 14, 2015, 1:13 PM
Cool Science Video: This is What a McDonald's Burger Looks Like in Your Stomach
April 7, 2015, 1:43 PM
Most Popular Articles
Exclusive: If Intel and Micron's "Xpoint" is 3D Phase Change Memory, Boy Did They Patent It
July 29, 2015, 10:52 PM
Quick Note: Apple Watch to Get Brick and Mortar Boost From Best Buy
July 27, 2015, 3:00 PM
Windows 10 to Get New Features in October Service Release 2 (SR2)
July 30, 2015, 5:50 PM
As iPad Sales Wane and Watch Flops, iPhone Saves Apple's Profit With Its Heroics
July 22, 2015, 6:13 PM
Editorial: Reddit Allows Itself to be Hijacked as a Hate Platform For Racist Bigots
July 21, 2015, 6:32 PM
Latest Blog Posts
Sceptre Airs 27", 120 Hz. 1080p Monitor/HDTV w/ 5 ms Response Time for $220
Dec 3, 2014, 10:32 PM
Costco Gives Employees Thanksgiving Off; Wal-Mart Leads "Black Thursday" Charge
Oct 29, 2014, 9:57 PM
"Bear Selfies" Fad Could Turn Deadly, Warn Nevada Wildlife Officials
Oct 28, 2014, 12:00 PM
The Surface Mini That Was Never Released Gets "Hands On" Treatment
Sep 26, 2014, 8:22 AM
ISIS Imposes Ban on Teaching Evolution in Iraq
Sep 17, 2014, 5:22 PM
More Blog Posts
Copyright 2015 DailyTech LLC. -
Terms, Conditions & Privacy Information