Artificial Pancreas Improves Glucose Control by 15%, Benefits Type 1 Diabetes Patients
January 30, 2013 5:55 PM
comment(s) - last by
Continual glucose monitor (left), pump worn on the belt that injects insulin under the patient’s skin (right), and a controller (a handheld smart phone)
(Source: Institut de recherches cliniques de Montreal)
Type 1 diabetics are expected to benefit from the new dual-hormone treatment
type 1 diabetic
is a full-time job, but a system that acts as an artificial pancreas could offer a bit of relief for those struggling to keep their glucose regulated.
An IRCM research team, led by Dr. Rémi Rabasa-Lhoret, have performed the first trial that compares an artifical pancreas system to a traditional diabetes treatment, and found that the artificial pancreas resulted in better glucose control.
The artificial pancreas is a dual-hormone system that
and glucagon automatically through the use of a continuous glucose monitor (CGM) and advanced algorithm.
The algorithm obtains data from the CGM, and it calculates the amount of insulin required. It will also calculate the required glucagon, if needed. Insulin lowers blood sugar while glucagon raises it, preventing the diabetic from experiencing hypoglycemia. Hypoglycemia is the result of blood sugar dropping too low, and can result in confusion and even loss of consciousness.
Once the insulin and glucagon is calculated, the CGM sends it to the wireless pump, and it automatically administers the proper dose of the hormones.
While pumps are available to diabetics today, the sensors must be checked frequently and the pump's dosage must be adjusted. This new system does everything without any interference from the person wearing it.
"Approximately two-thirds of patients don't achieve their target range with current treatments," said Dr. Rabasa-Lhoret. "The artificial pancreas could help them reach these targets and reduce the risk of hypoglycemia, which is feared by most patients and remains the most common adverse effect of insulin therapy. In fact, nocturnal hypoglycemia is the main barrier to reaching glycemic targets."
In the study, 15 type 1 diabetic adults that used insulin pumps for at least three months prior to the study were sent to IRCM's facility for two, 15-hour visits. During the visits, their glucose levels were monitored as they exercised on a stationary bike. They were also given an evening meal and a snack, and were sent to bed.
It turns out that the addition of glucagon and the algorithm for calculated release helped participants avoid hypoglycemia during the night. In fact, those with the dual-hormone treatment had 15 percent better glucose control than those with conventional pump treatment.
the artificial pancreas
had an 8-fold reduction in the risk of hypoglycemia, and a 20-fold reduction in the risk of hypoglycemia during the night.
This article is over a month old, voting and posting comments is disabled
RE: Become a Diabetes Warrior
2/1/2013 6:42:22 AM
Have you ever tried cutting Carbohydrates out of your diet completely?
You have to tools available to you to see how your blood sugar levels will react.
Why keep eating things your body can't process? And just stick with things your body can!
"Let's face it, we're not changing the world. We're building a product that helps people buy more crap - and watch porn." -- Seagate CEO Bill Watkins
FDA Releases New Guidelines to Speed Up Artificial Pancreas Development
December 2, 2011, 1:32 PM
Researchers Use Stem Cells to Treat Diabetes in Mice
February 21, 2008, 1:05 PM
Crunch Time For Diabetes Research
June 29, 2007, 12:54 AM
Quick Note: Drone Loses Fight to the Death With Kangaroo
December 23, 2014, 3:28 PM
Campbell's Monkeys Found to Use Different Dialects to Describe Local Threats
December 22, 2014, 3:52 PM
Scientist Confirm Men are More Likely to Die in "Idiotic" Ways
December 17, 2014, 1:07 PM
Shoppers Surprised to Find Cards Against Humanity's Bullsh*t is Real Feces
December 16, 2014, 11:14 PM
Air Force Worries Hot Fuel Could Harm F-35, "Proactively" Paints Trucks Shiny
December 11, 2014, 9:06 AM
McDonald's is Testing Tablet-Based Burger Customization at 30 Franchises
December 10, 2014, 11:30 AM
Most Popular Articles
Paramount Bans Team America Screenings, Cowers Submissively to North Korea
December 18, 2014, 10:26 PM
Android-Powered BLU Studio 7.0 Claims to be the "World's Largest Smartphone"
December 19, 2014, 2:40 PM
News Corp's Fox is Terrified of North Korea, Kills Upcoming Steve Carell Film
December 18, 2014, 4:09 PM
Amazon's Kindle Fire HDX 8.9 Drops to $299 (30 Percent Off) for a Day
December 22, 2014, 10:57 AM
Miyamoto: Nintendo is Prepping Successor to Troubled Wii U
December 22, 2014, 6:28 PM
Latest Blog Posts
Sceptre Airs 27", 120 Hz. 1080p Monitor/HDTV w/ 5 ms Response Time for $220
Dec 3, 2014, 10:32 PM
Costco Gives Employees Thanksgiving Off; Wal-Mart Leads "Black Thursday" Charge
Oct 29, 2014, 9:57 PM
"Bear Selfies" Fad Could Turn Deadly, Warn Nevada Wildlife Officials
Oct 28, 2014, 12:00 PM
The Surface Mini That Was Never Released Gets "Hands On" Treatment
Sep 26, 2014, 8:22 AM
ISIS Imposes Ban on Teaching Evolution in Iraq
Sep 17, 2014, 5:22 PM
More Blog Posts
Copyright 2014 DailyTech LLC. -
Terms, Conditions & Privacy Information