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The weekly injection removed 80 percent of senile plaques that cause Alzheimer's

Canadian researchers have come one giant step closer to finding treatment for those with Alzheimer's disease, and even a preventative vaccine.

The team of researchers hail from Université Laval, CHU de Québec, and pharmaceutical firm GlaxoSmithKline (GSK), and was led by Dr. Serge Rivest, professor at Université Laval's Faculty of Medicine and researcher at the CHU de Québec research center.

A key part of Alzheimer's disease is the production of a toxic molecule called amyloid beta. The body's defenders, called microglial cells, cannot eliminate amyloid beta, and that's when senile plaques are formed.

But the new study gives the brain's immune cells a boost through monophosphoryl lipid A, called MPL, which is a vaccine that has already been proven safe through its use with GSK.

After giving mice with Alzheimer's symptoms weekly injections of MPL for 12 weeks, about 80 percent of senile plaques were eliminated. Also, the mice showed improvement in cognitive function.

According to the team, the MPL injection could not only slow the progression of the disease in patients already showing symptoms, but also be used as a preventative vaccine for those at risk.

Last September, the cancer drugs erlotinib (Tarceva) and gefitinib (Iressa) were used to cure Alzheimer's in fruit flies and rats.

Source: Science Daily



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RE: Sign Me Up!
By Ytsejamer1 on 1/16/2013 11:00:15 AM , Rating: 1
I agree with your first sentiment 100%...this would be great. I always wonder about when possible "cures" or treatments are mentioned. Drug companies don't want to cure anything, they want to treat symptoms. That's their business. They don't want people getting healthy.

As for the other related wit...kind of funny. I remember telling my aunt a funny joke about the disease. She was taking care of my poor grandmother who was losing it completely. At some point, you have to make a joke and get a smile where you can. It's a horrendous disease to watch develop in a loved one.

The joke is...or paraphrased. Why is Easter an Alzheimer's favorite holiday? Answer: You can hide your own Easter eggs.


RE: Sign Me Up!
By unplug on 1/16/2013 11:31:22 AM , Rating: 2
/crickets


RE: Sign Me Up!
By Ytsejamer1 on 1/16/2013 11:57:55 AM , Rating: 2
fair enough...i thought it was funny when I heard it. Oh well.


RE: Sign Me Up!
By DaveLessnau on 1/16/2013 12:12:40 PM , Rating: 2
I try to put a good spin on it, too. Instead of Easter Eggs, I just tell myself it'll let me save money on books. I can keep re-reading the ones I have instead of buying new ones.

Recently, I re-read a book that I KNOW I've read before. I remembered not one word, not one event, not one plotline (not one jot or tittle) in the whole thing. That's scary.


RE: Sign Me Up!
By Ramstark on 1/16/2013 12:50:13 PM , Rating: 3
Hell it is. This is the most scary thing for me, that one day, I watch my son directly to his eyes and not know who he is or why he is worried.
We humans are all about our minds, if we lose it in a way that you forget everything (the good things and the bad things) then there is no point in living anymore, at least that my opinion. I'd rather die than forget.
I'll be following this "vaccine" close, when it is available, I will take it undoubtedly.


RE: Sign Me Up!
By Nutzo on 1/16/2013 11:39:43 AM , Rating: 2
I think you need to add a little more tin foil to your hat...

Drug companies don't want to cure anything??
I guess all the cures, vacines, etc they have come out with over the past decades must be my imagination.
The basic truth is that the Drug companies want to make money. A "cure" is likely to cost more than an initial treatment, since they have to recoupe the development cost over a much shorter treatment period.


RE: Sign Me Up!
By gamerk2 on 1/16/2013 11:42:04 AM , Rating: 2
To be fair, the Federal government has to reimburse medical companies to create vaccines, because they aren't profitable. As a result, most Vaccine research is done in Medical Labs, not by Medico's.


RE: Sign Me Up!
By Omega215D on 1/16/2013 12:55:17 PM , Rating: 2
People like this are the reason why some illnesses are making a comeback and possibly why this flu season seems to be pretty bad (that and also many city folk are slobs).


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