Embryonic Stem Cells Make Damaged Artery Functional Again
January 13, 2013 1:45 PM
comment(s) - last by
Embryonic stem cells from baboons produced a fully functional artery
Texas scientists have used embryonic stem cells to heal a severely damaged
in a baboon.
A team from the Texas Biomedical Research Institute in San Antonio, led by John L. VandeBerg, Ph.D., took embryonic stem cells from baboons to produce a fully functional artery.
To do this, the team extracted cells that line the surface of a part of an artery and
replaced them with cells
that were derived from embryonic stem cells. Both ends of the arterial segment were then connected to plastic tubing inside a bioreactor, which encourages cells to grow.
Fluid was then pumped through the artery under pressure to mimic blood, and a different fluid was then used to soak the outside of the artery. Only three days later, the inner surface began to regenerate, and after two weeks, the inside of the artery was completely restored to a functional state.
The team even stripped another artery without placing the stem cells inside to see if it was the stem cells that did the rejuvenating. The artery without
the stem cells
didn't heal and never became functional.
"We first cultured the stem cells in petri dishes under special conditions to make them differentiate into cells that are the precursors of blood vessels, and we saw that we could get them to form tubular and branching structures, similar to blood vessels," said VandeBerg. "Just think of what this kind of treatment would mean to a patient who had just suffered a heart attack as a consequence of a damaged coronary artery. And this is the real potential of stem cell regenerative medicine -- that is, a treatment with stem cells that regenerates a damaged or destroyed tissue or organ."
This study appeared in the
Journal of Cellular and Molecular Medicine
This article is over a month old, voting and posting comments is disabled
RE: Basic maintenance.
1/15/2013 8:44:05 AM
"Ok, so tell me, how is an ordinary person supposed to conduct a 5 year scientific trial that meets your expectations? It just won't happen. The nearest I can do is a one person trial, which is exactly what I am doing, and what those other people are doing."
of course, an individual with no medical training, no funding and no trial support cannot produce high quality scientific research.
thats why we have research departments in all major universities.
the individual cannot be expected to widely read the literature and produce their own considered opinion - this is why we have systematic reviews and metaanalyses.
the individual cannot even really be expected to read and understand the results of systematic reviews - this is why we have doctors - you pay them to do this work for you and you have to trust them to give you the best most honest advice.
if you dont have this sense of trust with your current doctor then i suggest you try to find another one. looking around trying to figure everything out yourself is frustrating and has a risk of causing harm (like steve jobs).
im not a specialist researcher in mesenchymal stem cells but i do know that there is a lot of FUD about stem cell research.
stem cells != embryonic stem cells
mesenchymal stem cells can be harvested from lots of different tissues - nothing has to die to produce them. there was an outcry about taking stem cells from embryos (which is very understandable) - however the overwhelming majority of stem cell research today does not involve any embryos. stem cells have been used for decades - e.g. a bone marrow transplant - a very common and old treatment for some cancers is essentially a transplant of multipotent stem cells.
with regard to eating a normal amount of a varied healthy diet, not smoking, not drinking too much and exercising regularly - this is common sense. you don't a doctor or anyone else to tell you that these are good things to do.
stem cell research (and by extension other research) is not being done so that we can live forever whilst chain smoking whilst guzzling down bucket after bucket of kfc.
its not an either/or situation. we should live nice clean healthy lifestyles and if research on top of that can produce treatments to further improve our quality of life then that can only be a good thing.
"Can anyone tell me what MobileMe is supposed to do?... So why the f*** doesn't it do that?" -- Steve Jobs
Stem Cell Transplant Treats Retinitis Pigmentosa in Mice, Restores Sight
January 8, 2013, 10:06 AM
Old Stem Cells Can Be Young Again Thanks to "Fountain of Youth"
November 28, 2012, 8:16 PM
Lab-Grown Arteries More Elastic Than Ever
February 1, 2011, 10:22 AM
SpaceX Falcon 9's Seventh Supply Mission to ISS Ends w/ Fiery Stage 1 Explosion
June 28, 2015, 1:10 PM
Cool Science Video: Glowing Millipede Prowls the Nevada Desert
May 18, 2015, 12:00 PM
Newly Discovered Costa Rican Glass Frog is Kermit's Doppelgänger
April 22, 2015, 11:26 AM
Researchers Hope to Find "Exotic" Lifeforms Inside Crater of Dinosaur Killing Meteor
April 14, 2015, 8:47 PM
Mathematician's Sociological Formulation May Explain the "Hipster Paradox"
April 14, 2015, 1:13 PM
Cool Science Video: This is What a McDonald's Burger Looks Like in Your Stomach
April 7, 2015, 1:43 PM
Most Popular Articles
Exclusive: If Intel and Micron's "Xpoint" is 3D Phase Change Memory, Boy Did They Patent It
July 29, 2015, 10:52 PM
Quick Note: Apple Watch to Get Brick and Mortar Boost From Best Buy
July 27, 2015, 3:00 PM
Windows 10 to Get New Features in October Service Release 2 (SR2)
July 30, 2015, 5:50 PM
As iPad Sales Wane and Watch Flops, iPhone Saves Apple's Profit With Its Heroics
July 22, 2015, 6:13 PM
Editorial: Reddit Allows Itself to be Hijacked as a Hate Platform For Racist Bigots
July 21, 2015, 6:32 PM
Latest Blog Posts
Sceptre Airs 27", 120 Hz. 1080p Monitor/HDTV w/ 5 ms Response Time for $220
Dec 3, 2014, 10:32 PM
Costco Gives Employees Thanksgiving Off; Wal-Mart Leads "Black Thursday" Charge
Oct 29, 2014, 9:57 PM
"Bear Selfies" Fad Could Turn Deadly, Warn Nevada Wildlife Officials
Oct 28, 2014, 12:00 PM
The Surface Mini That Was Never Released Gets "Hands On" Treatment
Sep 26, 2014, 8:22 AM
ISIS Imposes Ban on Teaching Evolution in Iraq
Sep 17, 2014, 5:22 PM
More Blog Posts
Copyright 2015 DailyTech LLC. -
Terms, Conditions & Privacy Information