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Embryonic stem cells from baboons produced a fully functional artery

Texas scientists have used embryonic stem cells to heal a severely damaged artery in a baboon.

A team from the Texas Biomedical Research Institute in San Antonio, led by John L. VandeBerg, Ph.D., took embryonic stem cells from baboons to produce a fully functional artery.

To do this, the team extracted cells that line the surface of a part of an artery and replaced them with cells that were derived from embryonic stem cells. Both ends of the arterial segment were then connected to plastic tubing inside a bioreactor, which encourages cells to grow.

Fluid was then pumped through the artery under pressure to mimic blood, and a different fluid was then used to soak the outside of the artery. Only three days later, the inner surface began to regenerate, and after two weeks, the inside of the artery was completely restored to a functional state.

The team even stripped another artery without placing the stem cells inside to see if it was the stem cells that did the rejuvenating. The artery without the stem cells didn't heal and never became functional.

"We first cultured the stem cells in petri dishes under special conditions to make them differentiate into cells that are the precursors of blood vessels, and we saw that we could get them to form tubular and branching structures, similar to blood vessels," said VandeBerg. "Just think of what this kind of treatment would mean to a patient who had just suffered a heart attack as a consequence of a damaged coronary artery. And this is the real potential of stem cell regenerative medicine -- that is, a treatment with stem cells that regenerates a damaged or destroyed tissue or organ."

This study appeared in the Journal of Cellular and Molecular Medicine.

Source: Science Daily

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RE: Basic maintenance.
By blue_urban_sky on 1/14/2013 12:42:27 PM , Rating: 2
Why can he not be a doctor, he seems level headed and knowledgeable. He has made good arguments against some very interesting views on how you can live forever if you have the right diet and meditate.

RE: Basic maintenance.
By ClownPuncher on 1/14/2013 1:04:46 PM , Rating: 2
I didn't see the "live forever with the right diet and meditation" comments. I saw some guy saying people should probably eat better.

RE: Basic maintenance.
By blue_urban_sky on 1/15/2013 5:58:08 AM , Rating: 2
I believe that the cause of a lot of disease and also what causes "old age" is the inability of the kidneys to remove particular types of waste from the blood.

My belief is there are particular types of food which help the kidneys to function correctly, so that the "selective blockage" is removed

RE: Basic maintenance.
By ClownPuncher on 1/15/2013 12:08:44 PM , Rating: 2
I didn't read too deeply into that. I read it as stating proper diet helps kidney functions and could allow you to live longer, which is true.

RE: Basic maintenance.
By blue_urban_sky on 1/15/2013 3:37:40 PM , Rating: 2
Yeah open to interpretation, but the other guy/gal was quite polite and argued well. This article was about the cutting edge of medical science and I too was taken aback at a post that seemed to say that the same effect could be achieved with diet. I don't wish to be drawn in but I just thought that you saying that he/she was not a doctor a bit off when they seemed to have a valid point.

Your interpretation is correct and it seems not in dispute, maybe the point was taken too literally.

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