Phase I of HIV Prevention Vaccine Clinical Trials Looks Promising
November 7, 2012 8:05 PM
comment(s) - last by
Over the course of Phase I, patients have not experienced negative effects while taking SAV001-H
for prevention has had a successful Phase I Clinical Trials in the United States, and is preparing to move on to Phase II and Phase III.
The preventative HIV vaccine (called SAV001-H) was developed by Dr. Chil-Yong Kang and a team of researchers at the University of Western Ontario's Schulich School of Medicine & Dentistry as well as researchers from Sumagen Co. Ltd. Unlike other HIV vaccines that underwent clinical trials, SAV001-H contains a killed whole HIV-1 rather than just one specific part of HIV as an antigen or genetic vaccine using recombinant DNA.
Phase I of clinical trials for the first HIV preventative vaccine started in March 2012.
Infected men and women
ranging from 18-50 years of age were separated into two groups, where one received SAV001-H and the other a placebo.
Over the course of Phase I, patients have not experienced negative effects while taking SAV001-H. This includes signs/symptoms, laboratory toxicities and local reactions.
"We have proven that there is no safety concern of SAV001-H in human administration and we are now prepared to take the next steps towards Phase II and Phase III clinical trials," said Dr. Dong Joon Kim, spokesperson for Sumagen. "We are delighted to be one step closer to the first commercialized HIV vaccine."
Also, interim data showed a large increase in HIV-1 antibody formations after SAV001-H was given to patients.
The humoral immune responses still need to be analyzed, but these initial results are promising. This could make SAV001-H the first commercially available HIV prevention vaccine in the United States at some point.
There has been great progress for preventative HIV drugs in the U.S. lately. Back in July, the U.S. Food and Drug Administration (FDA) approved the
HIV prevention pill called "Truvada."
University of Western Ontario
This article is over a month old, voting and posting comments is disabled
RE: I Already Have My HIV Prevention Vaccine
11/10/2012 2:39:45 PM
Not to mention that HIV-1M has been calculated to have been around since at least the early 1900's, and an estimated 3 million people or so around the world are affected by it annually. It's sad that I can tell when my fellow American's post by their ethnocentrism. Hey self-indulged children, guess what? The world is bigger and more important than just you.
"This is from the DailyTech.com. It's a science website." -- Rush Limbaugh
New Sensor Allows Naked Eye to See Early Detection Test Results for Diseases
October 30, 2012, 7:20 PM
New Polymer "PEI" Strengthens Vaccines Against HIV/Herpes/Flu
August 28, 2012, 10:45 AM
FDA Approves HIV Prevention Pill "Truvada"
July 16, 2012, 11:01 PM
United Airlines Puts Boeing's 787 Dreamliner Back in Service
May 20, 2013, 2:52 PM
Obama to "Clarify" His Position on Killing Americans With Drone Strikes
May 20, 2013, 11:22 AM
High School Student Creates Storage Device that Can Charge in 20 Seconds
May 20, 2013, 6:51 AM
Obama Admin Looks to Revive Bill for Greater Media Protection in Wake of AP Controversy
May 16, 2013, 1:47 PM
Notre Dame Designs Camera to Detect Age of Bruise for Abuse Checks
May 16, 2013, 9:05 AM
Report: Climate Change Could Wash Away Historic Jamestown Site Within 100 Years
May 15, 2013, 5:39 PM
Most Popular Articles
Windows 8.1 Will Be Free; Microsoft Holds Onto Struggling ARM Variant
May 14, 2013, 2:57 PM
Google Announces "Pure" Galaxy Nexus S4 for $649, Android Updates
May 15, 2013, 1:42 PM
Bill Gates Gets Teary-Eyed While Discussing Steve Jobs, Shows Off Life-Saving Tech on 60 Minutes
May 13, 2013, 12:30 PM
U.S. Federal Traffic Board Wants to Make Drunk Driving Threshold Far Harsher
May 15, 2013, 11:32 AM
Google's Eric Schmidt: "Don't Be Evil" was Stupid
May 14, 2013, 11:00 AM
Latest Blog Posts
Quick Note: Sony "Teases" PS4 Ahead of Xbox Reveal in New Video
May 20, 2013, 12:33 PM
Nokia Introduces Instagram-Like App of Its Own to Help Lumia Sales
May 20, 2013, 7:10 AM
Parents of Pre-Teen Drivers Commonly Practice Distracted Driving Says Study
May 9, 2013, 7:16 AM
Apple's iOS 7 Running Into Internal Delays Due to Massive Overhaul
May 1, 2013, 4:26 PM
Elon Musk Willing to Spend More Money on Widening of 405 Freeway
Apr 26, 2013, 7:28 PM
More Blog Posts
Copyright 2013 DailyTech LLC. -
Terms, Conditions & Privacy Information