Phase I of HIV Prevention Vaccine Clinical Trials Looks Promising
November 7, 2012 8:05 PM
comment(s) - last by
Over the course of Phase I, patients have not experienced negative effects while taking SAV001-H
for prevention has had a successful Phase I Clinical Trials in the United States, and is preparing to move on to Phase II and Phase III.
The preventative HIV vaccine (called SAV001-H) was developed by Dr. Chil-Yong Kang and a team of researchers at the University of Western Ontario's Schulich School of Medicine & Dentistry as well as researchers from Sumagen Co. Ltd. Unlike other HIV vaccines that underwent clinical trials, SAV001-H contains a killed whole HIV-1 rather than just one specific part of HIV as an antigen or genetic vaccine using recombinant DNA.
Phase I of clinical trials for the first HIV preventative vaccine started in March 2012.
Infected men and women
ranging from 18-50 years of age were separated into two groups, where one received SAV001-H and the other a placebo.
Over the course of Phase I, patients have not experienced negative effects while taking SAV001-H. This includes signs/symptoms, laboratory toxicities and local reactions.
"We have proven that there is no safety concern of SAV001-H in human administration and we are now prepared to take the next steps towards Phase II and Phase III clinical trials," said Dr. Dong Joon Kim, spokesperson for Sumagen. "We are delighted to be one step closer to the first commercialized HIV vaccine."
Also, interim data showed a large increase in HIV-1 antibody formations after SAV001-H was given to patients.
The humoral immune responses still need to be analyzed, but these initial results are promising. This could make SAV001-H the first commercially available HIV prevention vaccine in the United States at some point.
There has been great progress for preventative HIV drugs in the U.S. lately. Back in July, the U.S. Food and Drug Administration (FDA) approved the
HIV prevention pill called "Truvada."
University of Western Ontario
This article is over a month old, voting and posting comments is disabled
11/7/2012 10:21:29 PM
Kind of like how I am Legend began
"Well, we didn't have anyone in line that got shot waiting for our system." -- Nintendo of America Vice President Perrin Kaplan
New Sensor Allows Naked Eye to See Early Detection Test Results for Diseases
October 30, 2012, 7:20 PM
New Polymer "PEI" Strengthens Vaccines Against HIV/Herpes/Flu
August 28, 2012, 10:45 AM
FDA Approves HIV Prevention Pill "Truvada"
July 16, 2012, 11:01 PM
Nail Polish May Soon be Able to Detect Date Rape Drugs
August 26, 2014, 7:57 AM
SpaceX Falcon 9-R Rocket Suffers Malfunction, Self-Destructs During Test Flight
August 23, 2014, 9:36 AM
Texas Chosen as Site for SpaceX's First Commercial Launchpad
August 5, 2014, 1:44 PM
South Carolina Prison Finds Crashed Drone Carrying Drugs, Phones
August 1, 2014, 2:49 PM
NASA's Mars 2020 Rover Gains Seven New Instruments for Exploration
August 1, 2014, 1:30 PM
NASA Opportunity Rover Breaks Record for Most Miles Traveled on Another Planet
July 29, 2014, 1:38 PM
Most Popular Articles
Numerous Leaks Detail 4.7" iPhone 6 Processor, RAM, Cellular and NFC Capabilities
August 29, 2014, 10:37 PM
Windows 9: "Upgrade Now" Button Coming for Enterprise Updates, ARM Preview in H1 2015
August 26, 2014, 8:00 PM
L.A. Unified School District’s Apple iPad Contract Canceled Following Heavy Criticism
August 26, 2014, 12:37 PM
Apple Builds Not-So-Secret Secret 3-Story Tower for iPhone 6/iWatch Unveil
August 28, 2014, 3:41 PM
Netflix Accuses Comcast of Ripping Off Customers, Files to Block Merger
August 26, 2014, 5:49 PM
Latest Blog Posts
Space Terrorism is a Looming Threat For the United States
Apr 23, 2014, 7:47 PM
Facebook Aims to Provide Internet to "Every Person in the World" with Drones, Satellites
Apr 1, 2014, 10:20 AM
Retail Mobile Sites Experience Outages in Light of Simplexity's Bankruptcy
Mar 14, 2014, 8:48 AM
Tesla vs. BMW: Who Has the Safer EV?
Feb 1, 2014, 2:56 PM
Justice Leaks Details of Next HTC One Two Flagship Phone
Dec 5, 2013, 4:04 PM
More Blog Posts
Copyright 2014 DailyTech LLC. -
Terms, Conditions & Privacy Information