Human Stem Cell Trial Repairs Jaw/Mouth Bone Deficiencies
August 1, 2012 3:36 PM
comment(s) - last by
severe jaw deficiency
The stem cells, which are tissue repair cells called ixmyelocel-T, are used to re-grow craniofacial tissue
Humans with jawbone deficiencies in need of dental implants could benefit from a
new stem cell trial
conducted by Michigan researchers.
Darnell Kaigler, study leader from the University of Michigan School of Dentistry, along with William Giannobile, co-author and director of the Michigan Center for Oral Health Research, and Aastrom Biosciences Inc. collaborated to create a stem cell-based method for bone regeneration.
"In patients with jawbone deficiencies who also have missing teeth, it is very difficult to replace the missing teeth so that they look and function naturally," said Kaigler. "This technology and approach could potentially be used to restore areas of bone loss so that missing teeth can be replaced with dental implants."
, which are tissue repair cells called ixmyelocel-T, are used to re-grow craniofacial tissue. They are taken from bone marrow from the patient's own hip and grown using Aastrom Biosciences Inc.'s proprietary system.
To put ixmyelocel-T to the test, the team conducted a human trial where 24 patients with jawbone deficiencies and missing teeth were split into two groups: one that received the stem cell treatment, and the other that received convention bone regeneration treatment.
The stem cells were placed into the mouth and jaw. Patients were observed after six and 12 weeks, and according to the results, those receiving the stem cell treatment experienced faster bone repair and greater bone density than those with traditional bone therapy. Also, the stem cell group required less secondary bone grafting for implants.
This type of treatment could be used for those born with defects or those who've suffered trauma or certain diseases. However, more clinical trials are required before these stem cell therapies can be used regularly.
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RE: Another Adult Stem Cell Win
8/2/2012 1:16:30 PM
Because cows are delicious, that's why.
RE: Another Adult Stem Cell Win
8/2/2012 2:41:37 PM
That they are!
A little OT but I think I'll share anyways: I made an awesome skillet burger last night and it is so easy any red-blooded Man should know how to do this.
It works best with frozen hamburger which you thaw, then start to pre-heat a frying pan/skillet with a nice lump of coconut oil plopped in it so it melts nicely, coating everything. (Coconut oil isn't nearly as bad for you as you'd think--well, the theory suggests at least).
You then make your patties and put them in the pan and sprinkle a nice amount of salt on them, covering with a lid afterwards. Let them cook for a few minutes (about five or six) on medium-low heat (I never get close to medium as they'll burn), then flip. After you flip, pour some more salt on them and cook for about two to three minutes. Add cheese (American is awesome), turn off the heat and let it melt, soaking in.
Done. Put on a bun (preferrably lightly toasted) and whatever else you'd like. Awesome, unhealthy goodness right there!
What's the whole point of this?
Well, simple, you wouldn't go next door chop up your neighbor, put them through a meat grinder, freeze them, thaw it back out and make a juicy burger using their meat, would you? If so... you need help, serious help.
Thus, cows are different from humans... in an edible, sane sense.
"I'd be pissed too, but you didn't have to go all Minority Report on his ass!" -- Jon Stewart on police raiding Gizmodo editor Jason Chen's home
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