Human Stem Cell Trial Repairs Jaw/Mouth Bone Deficiencies
August 1, 2012 3:36 PM
comment(s) - last by
severe jaw deficiency
The stem cells, which are tissue repair cells called ixmyelocel-T, are used to re-grow craniofacial tissue
Humans with jawbone deficiencies in need of dental implants could benefit from a
new stem cell trial
conducted by Michigan researchers.
Darnell Kaigler, study leader from the University of Michigan School of Dentistry, along with William Giannobile, co-author and director of the Michigan Center for Oral Health Research, and Aastrom Biosciences Inc. collaborated to create a stem cell-based method for bone regeneration.
"In patients with jawbone deficiencies who also have missing teeth, it is very difficult to replace the missing teeth so that they look and function naturally," said Kaigler. "This technology and approach could potentially be used to restore areas of bone loss so that missing teeth can be replaced with dental implants."
, which are tissue repair cells called ixmyelocel-T, are used to re-grow craniofacial tissue. They are taken from bone marrow from the patient's own hip and grown using Aastrom Biosciences Inc.'s proprietary system.
To put ixmyelocel-T to the test, the team conducted a human trial where 24 patients with jawbone deficiencies and missing teeth were split into two groups: one that received the stem cell treatment, and the other that received convention bone regeneration treatment.
The stem cells were placed into the mouth and jaw. Patients were observed after six and 12 weeks, and according to the results, those receiving the stem cell treatment experienced faster bone repair and greater bone density than those with traditional bone therapy. Also, the stem cell group required less secondary bone grafting for implants.
This type of treatment could be used for those born with defects or those who've suffered trauma or certain diseases. However, more clinical trials are required before these stem cell therapies can be used regularly.
This article is over a month old, voting and posting comments is disabled
8/2/2012 12:17:47 PM
Look up the work of Weston A. Price, most dental/facial development problems are caused by nutrient deficiency in both the mother while pregnant and in the child's diet while growing. I would bet a million dollars that woman's facial development was not a genetic problem, but a lack of adequate nutrition in her and her mother's diet, especially Vitamin K2.
If all future mothers in America got enough Vitamin K2 in their diet starting today, and made sure their kids did as well, the dental industry would start to see a seriously huge drop in new young clients within the next couple decades...
"So if you want to save the planet, feel free to drive your Hummer. Just avoid the drive thru line at McDonalds." -- Michael Asher
Stem Cell Technique Produces Colonies of Blood Cells from Patient's Existing Cells
July 18, 2011, 10:15 AM
Researchers Announce First Clinical Trial for Stem Cell Therapy
October 12, 2010, 10:19 AM
Nail Polish May Soon be Able to Detect Date Rape Drugs
August 26, 2014, 7:57 AM
SpaceX Falcon 9-R Rocket Suffers Malfunction, Self-Destructs During Test Flight
August 23, 2014, 9:36 AM
Texas Chosen as Site for SpaceX's First Commercial Launchpad
August 5, 2014, 1:44 PM
South Carolina Prison Finds Crashed Drone Carrying Drugs, Phones
August 1, 2014, 2:49 PM
NASA's Mars 2020 Rover Gains Seven New Instruments for Exploration
August 1, 2014, 1:30 PM
NASA Opportunity Rover Breaks Record for Most Miles Traveled on Another Planet
July 29, 2014, 1:38 PM
Most Popular Articles
Microsoft's Surface 2 Tablet Family Gets a $100 Price Cut
August 25, 2014, 1:16 AM
Owner of "Decepticon" Maserati Ordered to Appear in Court This Thursday
August 25, 2014, 7:55 AM
LG Posts Teaser Video of Its “Round Face” G Watch R Smartwatch, Set for IFA Lauch
August 24, 2014, 2:49 PM
Windows 9: "Upgrade Now" Button Coming for Enterprise Updates, ARM Preview in H1 2015
August 26, 2014, 8:00 PM
Second ZMapp-Treated Patient Dies of Ebola, Supplies Run Out
August 25, 2014, 7:03 PM
Latest Blog Posts
Space Terrorism is a Looming Threat For the United States
Apr 23, 2014, 7:47 PM
Facebook Aims to Provide Internet to "Every Person in the World" with Drones, Satellites
Apr 1, 2014, 10:20 AM
Retail Mobile Sites Experience Outages in Light of Simplexity's Bankruptcy
Mar 14, 2014, 8:48 AM
Tesla vs. BMW: Who Has the Safer EV?
Feb 1, 2014, 2:56 PM
Justice Leaks Details of Next HTC One Two Flagship Phone
Dec 5, 2013, 4:04 PM
More Blog Posts
Copyright 2014 DailyTech LLC. -
Terms, Conditions & Privacy Information