Human Stem Cell Trial Repairs Jaw/Mouth Bone Deficiencies
August 1, 2012 3:36 PM
comment(s) - last by
severe jaw deficiency
The stem cells, which are tissue repair cells called ixmyelocel-T, are used to re-grow craniofacial tissue
Humans with jawbone deficiencies in need of dental implants could benefit from a
new stem cell trial
conducted by Michigan researchers.
Darnell Kaigler, study leader from the University of Michigan School of Dentistry, along with William Giannobile, co-author and director of the Michigan Center for Oral Health Research, and Aastrom Biosciences Inc. collaborated to create a stem cell-based method for bone regeneration.
"In patients with jawbone deficiencies who also have missing teeth, it is very difficult to replace the missing teeth so that they look and function naturally," said Kaigler. "This technology and approach could potentially be used to restore areas of bone loss so that missing teeth can be replaced with dental implants."
, which are tissue repair cells called ixmyelocel-T, are used to re-grow craniofacial tissue. They are taken from bone marrow from the patient's own hip and grown using Aastrom Biosciences Inc.'s proprietary system.
To put ixmyelocel-T to the test, the team conducted a human trial where 24 patients with jawbone deficiencies and missing teeth were split into two groups: one that received the stem cell treatment, and the other that received convention bone regeneration treatment.
The stem cells were placed into the mouth and jaw. Patients were observed after six and 12 weeks, and according to the results, those receiving the stem cell treatment experienced faster bone repair and greater bone density than those with traditional bone therapy. Also, the stem cell group required less secondary bone grafting for implants.
This type of treatment could be used for those born with defects or those who've suffered trauma or certain diseases. However, more clinical trials are required before these stem cell therapies can be used regularly.
This article is over a month old, voting and posting comments is disabled
8/2/2012 12:17:47 PM
Look up the work of Weston A. Price, most dental/facial development problems are caused by nutrient deficiency in both the mother while pregnant and in the child's diet while growing. I would bet a million dollars that woman's facial development was not a genetic problem, but a lack of adequate nutrition in her and her mother's diet, especially Vitamin K2.
If all future mothers in America got enough Vitamin K2 in their diet starting today, and made sure their kids did as well, the dental industry would start to see a seriously huge drop in new young clients within the next couple decades...
"Intel is investing heavily (think gazillions of dollars and bazillions of engineering man hours) in resources to create an Intel host controllers spec in order to speed time to market of the USB 3.0 technology." -- Intel blogger Nick Knupffer
Stem Cell Technique Produces Colonies of Blood Cells from Patient's Existing Cells
July 18, 2011, 10:15 AM
Researchers Announce First Clinical Trial for Stem Cell Therapy
October 12, 2010, 10:19 AM
Crowdfunded Sex Toy Lets You Control the Action From Your Wii Nunchuk
January 15, 2015, 3:42 PM
Elon Musk Plays Warcraft; But Still Finds Time to Sleep, Build a Mars Colony Ship
January 6, 2015, 9:54 PM
SpaceX Scrubs Falcon 9 Launch to ISS, Barge Landing Test, Friday Redo Targeted
January 6, 2015, 4:02 PM
Quick Note; Wreckage of Malaysian-Owned Passenger Jet Found
December 30, 2014, 12:42 PM
Quick Note: Drone Loses Fight to the Death With Kangaroo
December 23, 2014, 3:28 PM
Campbell's Monkeys Found to Use Different Dialects to Describe Local Threats
December 22, 2014, 3:52 PM
Most Popular Articles
Microsoft Shows Off Latest Windows 10 Build, Preps it for Next Week Release
January 21, 2015, 2:57 PM
Under the Hood: How DirectX 11.3 and 12 Will Supercharge Windows 10 Gaming
January 23, 2015, 12:34 PM
Police are Using New Handheld Radar Sensors to Peer Into Houses w/out Warrant
January 20, 2015, 1:35 PM
BlackBerry CEO Claims Devs are Violating Net Neutrality by Not Supporting BB10
January 22, 2015, 4:37 PM
Report: Samsung Drops Snapdragon 810 From Galaxy S6, Will Use Its Own Chips
January 21, 2015, 1:47 PM
Latest Blog Posts
Sceptre Airs 27", 120 Hz. 1080p Monitor/HDTV w/ 5 ms Response Time for $220
Dec 3, 2014, 10:32 PM
Costco Gives Employees Thanksgiving Off; Wal-Mart Leads "Black Thursday" Charge
Oct 29, 2014, 9:57 PM
"Bear Selfies" Fad Could Turn Deadly, Warn Nevada Wildlife Officials
Oct 28, 2014, 12:00 PM
The Surface Mini That Was Never Released Gets "Hands On" Treatment
Sep 26, 2014, 8:22 AM
ISIS Imposes Ban on Teaching Evolution in Iraq
Sep 17, 2014, 5:22 PM
More Blog Posts
Copyright 2015 DailyTech LLC. -
Terms, Conditions & Privacy Information