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Medical breakthrough could allow Hawking and other mostly paralyzed people to "speak" easier

Amyotrophic lateral sclerosis, a degenerative neural disease, robbed brilliant physicist Stephen Hawking of his movement and speech.  Today Professor Hawking, 70, communicates via a custom speech generation device, which translates his cheek twitches into speech.  It takes hours for this vestige of the physicist's neuromuscular response, carefully catalogued by infrared sensors, to generate a couple sentences in reply to a question.

I. Giving the Severely Paralyzed a Voice

But a San Diego, California-based startup named NeuroVigil, Inc. is working to give Professor Hawking easy access to something nature law denied him – unencumbered speech.  The company has developed a device called iBrain.  

The mere size of a matchbox, the head-mounted device shares some similarities with so-called "brain mice", used by gamers.  However, it provides far more precise scans of brain wave activity, thanks to its SPEARS algorithm.  

It detects different kinds of gamma waves -- like the kind generated when a paralyzed person tries to will their limbs to move.  The sensor also picked up clear profiles of alpha waves -- brain activity associated with wakeful relaxation -- when Professor Hawking closed his eyes.

The device is already being considered as a potential tool in studying and combatting post-traumatic stress disorder (PSD), sleep apnea, autism, and a whole host of brain conditions.  It's even been used in a clinical test to study the effects of experimental drugs on the brain.

iBrain
A first-generation iBrain device [Image Source: NeuroVigil]

But its most potent uses may lie in granting speech and mobility to the paralyzed.  By associating willful thoughts with words -- or possibly letters -- a speech system could be developed that far outpaces the painstakingly slow dictation systems that fully paralyzed individuals like Professor Hawking use.

Alternatively, the system could be used to order movements from an exoskeleton, which would grant individuals like Professor Hawking mobility.  Ironically, such a system is remarkably similar to one depicted in a 1997 parody article in The Onion.

In a Telegraph interview with Philip Low, NeuroVigil's founder, chairman, and CEO, he describes the tests on Professor Hawking, stating, "We'd like to find a way to bypass his body, pretty much hack his brain."

For now the tests on Professor Hawking have been just that -- tests.  But Mr. Low and others are working to "productize" the results, to make a basic speech demonstration.

II. From Tragedy to Triumph

For Mr. Low, that demonstration will mark the culmination of decades of devotion to his quest to unlock the brain's secrets via wearable brain-wave monitors.  

Stephen Hawking
Stephen Hawking may be able to benefit from the novel device and has helped to test it.
[Image Source: Ted S. Warren / AP]

His father suffered tragically from a tragic brain-related side effect of medication.  He recalls in an MSNBC interview, "I would have loved to see this 20 years ago, when my father suffered from a side effect of a commonly used sleep drug.  He threatened someone with a weapon ... a gun, actually. And it destroyed our family."

His father was convicted of a criminal act, but later pardoned, given the circumstances.  Still the incident stuck with Mr. Low.

He put $240,000 USD on his credit cards to fund NeuroVigil.  It took him years of studying brain waves in bird brains to develop the first generation iBrain.  But the sacrifices paid off.  Now he's courting some of the world's top investors and brains and is set to debut his slimmest model yet.  His iBrain 3 will launch next year, pushing the envelope even further.

He describes, "It will be about the size of a U.S. quarter.  People will be able to check their brain activity much like you or I can check our blood pressure.

It's very ironic that an algorithm I initially developed to analyze the brain patterns of birds has found its way to dealing with Stephen Hawking's brain patterns, the U.S. military and autistic children."

Source: MSNBC



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How much?
By wordsworm on 6/26/2012 8:50:01 PM , Rating: 2
Sounds like it could be a pretty cool way of controlling stuff. If one can control a machine with it, it could be conceivable to put such a device to a myriad of uses: ie., control a robot, ventriloquism, drive a car, are a few I can think of.




RE: How much?
By StormyKnight on 6/27/2012 7:14:36 AM , Rating: 2
Battletech neuro-helmet.


RE: How much?
By ViroMan on 6/27/2012 1:15:41 AM , Rating: 2
I am more interested in using it to control a robot I can fornicate with.


RE: How much?
By MrBlastman on 6/27/2012 12:38:05 PM , Rating: 5
The only problem with fornication robots is they are predictable and lack spontaneity.

For example, when you lay down with them, you already know that not only are they going to polish your knob orally, but they are also about to willingly swallow at the summit of the act.

I mean, I know it would be utterly legal to smack your bits up while exploring the posterior region as well... but honestly, wouldn't it get boring?

At least with a real woman you never know what you're going to get (well, other than possibly getting some), but at least, barring you insult her haircut, speak poorly of her mother, forget to complement her on the minor re-arrangement of furniture in the house that is barely noticeable, forget that this day was the first day that you and her shared a nepalese wolfhound shishinoble... you know they aren't going to go awry and squeeze/bite/etc too hard and wreck your happyman...

Oh heck, you get the idea... Or maybe you don't. Or maybe I don't. :) Darn women are so confusing.

Maybe a robot ain't so bad after all.


RE: How much?
By Makaveli on 6/27/2012 3:13:17 PM , Rating: 2
I know you joking but that's pretty sad.

There are plenty of real women out there you should get out more.

Flesh better than metal when it comes to fornication!


RE: How much?
By ViroMan on 6/29/2012 1:53:41 AM , Rating: 2
Metal does what I inform it "should" do. Besides they have flesh lights that are pretty damn good... put that texture all over the robot body and you got yourself one hell of a love bot.


RE: How much?
By Visual on 6/27/2012 9:58:03 AM , Rating: 2
Why do people always think of the boring and mundane applications of BCI tech and not the really revolutionary ones?

Playing games, controlling a robot for work or for the military or such is everyone's first idea. But it is nothing special. Even helping a handicapped person get restored movement, while cool and useful and a Good Thing (tm), is still a very limited and near-sighted goal...

The true revolution such devices can bring is in non-conventional computer inputs for various application. We should not be aiming to simply replace the mouse with moving the same pointer with our mind on a 2d screen - why limit ourselves with just two degrees of freedom if the brain could be capable of much more... Instead, imagine seemlessly controlling a 3d viewpoint - that is 3 degrees of freedom for position plus 3 for direction. At the same time, maybe even also control the position of an object in the scene, or several. And there is no need to limit it to controlling motion as such too - we could just as easily control size, shape, pressure, color, tone or whatever one can think of in any complex application.

It would be a start of a new era in digital art... design, modelling, 2d and even 3d paintings, music... and probably things we can not even imagine or predict yet.

This applies to text input and communication as well. Currently we can only imagine traditional language input, speech synthesis, etc... but a wide use of BCI tech could one day lead us to new ways of communication that are hard to imagine, explain or predict from our current point of view. Eventually we could end up communicating by sharing raw thoughts, feelings, emotions, ideas, memories... sounds, images, situations, actions... Representing those in a traditional language might be inaccurate, ambigous, slow and inefficient but might become fast, easy and accurate with BCI and some future "digital" language.

And lastly, if we really manage to improve the expressiveness, accuracy and speed of communicating between ourselves, I believe that may even lead to improved thinking abilities in the future generation. Consider for a moment that we all learn to think in parallel with learning to communicate as we grow up. A lot of our thoughts are actually in the form of an "inner voice" speaking natural language. If that can be improved... the BCI revolution will be bigger than anything in previous history.


RE: How much?
By augiem on 6/27/2012 1:37:03 PM , Rating: 2
Who says nobody thinkg of those things? Neural links are a staple of sci-fi. From as simple sharing of knowledge (The Link in Stargate SG1 and Outer Limits), mind control to full blown virtual reality networking (Matrix, SG1/Atlantis, etc). I'm sure it goes far deeper in sci fi novels.

Problem is, that kind of stuff is so many lightyears more complex than what they're experimenting with now -- you're talking a direct data connection with the brain (in and out) vs mapping a few recognizable brain wave patterns to predefined functions (speech, controlling a pointer, etc). So, yeah, everyone thinks of the exotic stuff, but the "mundane" things are far more realistic, immediately useful, and we'll actually have a chance to see some of them in our lifetimes as opposed to sci-fi dreamings hardly related to the current research.


RE: How much?
By Pitbull0669 on 6/27/2012 3:40:44 PM , Rating: 1
Ya know its totaly Cray I just had a Dream aout this guy and that this was gonna give him the ability to way more than he can now. ..Very strqange.


RE: How much?
By geddarkstorm on 6/27/2012 11:55:56 AM , Rating: 2
Add to this, that the current goal is to reduce it from the already amazingly small size of a matchbox down to a quarter? You could put these things anywhere. It's just stunning. What an enormous leap forward for neural interfaces!

Not to mention, this guy's personal story too is pretty inspiring. Just, wow. Now that's a man on a mission.


Name choice
By Solandri on 6/27/2012 7:26:23 AM , Rating: 5
quote:
The company has developed a device called iBrain.

Apple lawsuit coming in 3... 2... 1...




RE: Name choice
By Visual on 6/27/2012 9:11:22 AM , Rating: 3
You misread, it is not called iNoBrain, so Apple has no case.


RE: Name choice
By AMDftw on 6/27/2012 7:06:23 AM , Rating: 2
Sure they have a case it has "i" in the front of word.


RE: Name choice
By Gondor on 6/27/2012 10:39:04 AM , Rating: 2
Alas, Apple has patent on both. In fact, they have patents on patents and patent lawsuits as well.


iBrain Mainframe
By ROTFLCOPTER on 6/27/2012 2:44:50 PM , Rating: 2
An interesting application would be to use these devices to create a brain save system, to store your thoughts and psyche. Maybe we can't get to the head in a jar thing, a la Futurama, but head on a screen might be workable.




RE: iBrain Mainframe
By geddarkstorm on 6/27/2012 12:01:40 PM , Rating: 2
Now that's starting to sound like a Space Opera.

But sadly that is likely not possible. The reason for that is you never use all your brain at once, but different parts are used for different occasions, yet all make up who you are. So how could you possible read all the latent areas?

Add to this that we can't scan all the brainwaves (even though this has advanced such abilities by leaps and bounds), or truly decode exactly what all of them mean (two people could have the same brainwaves, but completely different meanings to them, as ultimately waves are just ion gate activity, but the meaning of that activity is determined by which neurons and which neurotransmitters those neurons are choosing to release).

To truly save state your brain, you'd have to get the meaning and configurations (including all latent synapses) of the 100 billion neurons in your brain, and the 1 trillion or so glial and astral support cells, which also do minor communications and communication modulation of the neurons. What makes up your brain is a staggering amount of connections; nothing we can even remotely begin to replicate let alone scan (how would we scan physical connections though bone and matter in 3D?).


RE: iBrain Mainframe
By MrBlastman on 6/27/2012 12:27:27 PM , Rating: 2
quote:
What makes up your brain is a staggering amount of connections; nothing we can even remotely begin to replicate let alone scan (how would we scan physical connections though bone and matter in 3D?).


I bet we'll be there soon enough. We're already making significant progress.

http://www.nih.gov/news/health/mar2012/nimh-29.htm


RE: iBrain Mainframe
By geddarkstorm on 6/27/2012 2:12:00 PM , Rating: 2
Well I'll be darned. I forgot about their technique to actually track the motion of water through the axons. 25% visible with improvements not in that study that have brought that up to 75% they say? Spectacular. The hardest parts are the cerebral cortex, that's where all the most interesting connections are, hidden in the folds. But wow, guess I underestimated our ingenuity. Bring all these together, and in another 20 years, maybe we will be able to save "snapshot" pictures of an individual brain in 3D. After that, we'd need resolution enough to see each individual synapse and dendrite orientation, but doesn't sound like that's far off.

Then we'd just need to get the genome and epigenenome, to see the profile of how the cells will respond, and to what degree they will respond, to a signal. And we may actually get close to a "savestate".

Hah, phenomenal.


Just how tragic is it?
By FITCamaro on 6/27/2012 7:51:39 AM , Rating: 3
quote:
His father suffered tragically from a tragic brain-related side effect of medication.


Fail.




RE: Just how tragic is it?
By bah12 on 6/27/2012 11:57:59 AM , Rating: 2
It's tragically tragic of course...duh!


By Doken44 on 7/1/2012 11:54:28 PM , Rating: 2
As the technologies of brain monitoring and robotic sensors advance, the only remaining tech that needs to be developed to completely replace a lost limb is a method to provide feedback directly to the nervous system.

I suppose battery tech needs improvement as well, but I can't imagine many people missing appendages being unwilling to strap on a battery pack of some sort.




"What would I do? I'd shut it down and give the money back to the shareholders." -- Michael Dell, after being asked what to do with Apple Computer in 1997














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