Canadian Researchers Find Way to Grow Stem Cells in Larger Quantities
April 9, 2012 2:15 PM
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The new suspension method allows stem cells to be collected in larger numbers instead of being scraped off of a surface
Researchers from the University of Toronto's Institute of Biomaterials and Biomedical Engineering (IBBME) have created a new method for
growing stem cells
in larger quantities.
David Fluri, a postdoctoral researcher at IBBME, and Peter Zandstra, a professor at IBBME, have developed a new suspension method for growing stem cells, which allows for the collection of greater numbers of stem cells and increases the chance of obtaining viable cells in a cost-effective way.
Traditionally, stem cells are grown on surfaces that need to be scraped and are then differentiated from other kinds of cells to avoid cell death. However, this method doesn't produce enough viable stem cells from each culture, and the high cost to use this method doesn't match the results.
But now, Fluri and Zandstra have combined the stem cell creation process with a bioreactor, which provides stable environments for such processes. The cells were also grown in suspension, making the process more stable and safer for
more viable cells
By doing this, mouse cells were reprogrammed into pluripotent stem cells, which can become any kind of cell. They were then changed into cardiac cells.
Fluri and Zandstra hope that this new technique can be used to eventually treat heart disease. It is designed to work with large scale processes and provide the quantity needed for successful stem cell research and drug development.
"This is an enabling technology," said Zandstra. "It takes something we showed we could do before at low efficiency but not at such numbers that could be used in manufacturing."
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RE: This could have been the US
4/11/2012 12:53:42 AM
Ah, the infamous and subjective personhood argument. You do know that not all fetuses develop at the same rate? So your 22 week rule is just a line in the sand that you drew based on some non-objective principles that YOU think matter more than others?
You are just a clump of a few trillion cells. I don't measure the value of a human based on how many cells they contain. Moral freaks like you do, though, and it shows your true colors.
Nice straw man about religion, as if it has anything to do with the biology of human reproduction.
Nice link. Prepare yourself for more:
"Human development begins at fertilization, the process during which a male gamete or sperm (spermatozoo developmentn) unites with a female gamete or oocyte (ovum) to form a single cell called a zygote. This highly specialized, totipotent cell marked the beginning of each of us as a unique individual."
Keith L. Moore, The Developing Human: Clinically Oriented Embryology, 7th edition. Philadelphia, PA: Saunders, 2003. pp. 16, 2. "Human development begins at fertilization, the process during which a male gamete or sperm (spermatozoo developmentn) unites with a female gamete or oocyte (ovum) to form a single cell called a zygote. This highly specialized, totipotent cell marked the beginning of each of us as a unique individual."
"A zygote is the beginning of a new human being (i.e., an embryo)."
Keith L. Moore, The Developing Human: Clinically Oriented Embryology, 7th edition. Philadelphia, PA: Saunders, 2003. pp. 16, 2.
"Development begins with fertilization, the process by which the male gamete, the sperm, and the femal gamete, the oocyte, unite to give rise to a zygote."
T.W. Sadler, Langman's Medical Embryology, 10th edition. Philadelphia, PA: Lippincott Williams & Wilkins, 2006. p. 11.
"[The zygote], formed by the union of an oocyte and a sperm, is the beginning of a new human being."
Keith L. Moore, Before We Are Born: Essentials of Embryology, 7th edition. Philadelphia, PA: Saunders, 2008. p. 2.
"Although life is a continuous process, fertilization (which, incidentally, is not a 'moment') is a critical landmark because, under ordinary circumstances, a new genetically distinct human organism is formed when the chromosomes of the male and female pronuclei blend in the oocyte."
Ronan O'Rahilly and Fabiola Müller, Human Embryology and Teratology, 3rd edition. New York: Wiley-Liss, 2001. p. 8.
"Human embryos begin development following the fusion of definitive male and female gametes during fertilization... This moment of zygote formation may be taken as the beginning or zero time point of embryonic development."
William J. Larsen, Essentials of Human Embryology. New York: Churchill Livingstone, 1998. pp. 1, 14.
"It is the penetration of the ovum by a spermatozoan and resultant mingling of the nuclear material each brings to the union that constitues the culmination of the process of fertilization and marks the initiation of the life of a new individual."
Clark Edward Corliss, Patten's Human Embryology: Elements of Clinical Development. New York: McGraw Hill, 1976. p. 30.
I could go on, but I hope by now you get the idea. You aren't arguing the science of human embryology, you are arguing about the attributed value of humans at a specific point in their development.
"A politician stumbles over himself... Then they pick it out. They edit it. He runs the clip, and then he makes a funny face, and the whole audience has a Pavlovian response." -- Joe Scarborough on John Stewart over Jim Cramer
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