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Neanderthals and Denisovans, two archaic hominid species, have been shown by genetic tests to have interbred with human migrants in Europe and Asia.  (Source: Corbis)

Researchers speculate that such sexual attractions between the species were rare, but that the children were much more genetically fit, so came to dominate the population.  (Source: Google Images)

The highest rates of Denisovan DNA occurrence were found in the DNA of natives of Papua New Guinea.  (Source: Flickr)

The immune proteins our hominid relatives gave to us during interbreeding made us hardier and more resist to potentially deadly infections.  (Source: Paul de Bakker)
Turns out Europeans and Asians may be the least "genetically pure" homo-sapiens

It turns out that European DNA, like that of Asians and Africans, has traces of archaic hominids mixed in with the familiar Homo sapien-specific stretches.

The sequencing of the Neanderthal genome
 has led to some incredible discoveries -- among them, that humans were having sex with Neanderthals.  A pair of new studies has shown that Neanderthal genes aren't evenly distributed throughout the entire human population -- rather some populations have more or less of them.

A new study, whose senior author is 
Peter Parham, a professor of cell biology, microbiology and immunology at the Stanford University School of Medicine, examines how interbreeding with our closely related hominids led to a superior human immune system.

Svante Pääbo, director of the Department of Genetics at the Max Planck Institute for Evolutionary Anthropology and senior author on the paper [abstract] detailing the original Neanderthal genome draft, suggests that one of two possibilities occurred.  Either migrants to Asian and Europe broadly had sex with Neanderthals or just a few did, but whose progeny survived in greater numbers, passing on the early hominids' genetic material.  Researchers believe the latter explanation is more likely the case.

Humans are thought to have migrated from Africa around 67,500 years ago, spreading to Asia and Europe.  In these regions they encountered Neanderthals and Denisovans -- another archaic hominid, who they at least occasionally engaged in sexual intercourse with.  Interbreeding is thought to have occurred starting around 50,000 years ago.

Those hairy charmers passed something valuable along to the migrants -- improved immunity.  Many of Eurasians'  HLA genes -- fast evolving human immune system components -- are thought to have been "borrowed" from the Neanderthal and Denisovan genome.

It found that one Denisovan-derived gene -- HLA-A  -- was 95 percent likely to occur in residents of Papua New Guinea, 70 percent in residents of China, 50 percent in Europe, and virtually non-present in Africa.

The genes are thought to have conferred improved survival rates on the migrants, as they gained defenses against local diseases, which took their archaic hominid co-inhabitants millennia to develop.

Africans, who never personally interbred with the Denisovans and Neanderthals did receive a bit of these genes second hand, from migrants who returned to the region around 10,000 years ago.  And they are thought to have an even stronger and more diverse immune system, as they bred with other species of archaic hominids
, which were native to Africa.

Previous studies have shown that non-Africans have around 4 percent Neanderthal genes, while Melanesians -- natives of Indonesia and the surrounding islands -- also have 4 to 6 percent of their genes derived from the Denisovans.

The study on the project is published
 [abstract] in the prestigious peer-reviewed journal Science.

The new work could offer some additional explanation of why Native Americans may have been so susceptible to diseases brought to the New World by Europeans and Africans.  Native Americans may have missed much of the interbreeding opportunities.  Thus while they may be the most "pure" examples of Homo sapiens DNA, that may have proved fatal to many of them.



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By theAfrican on 8/27/2011 4:23:29 PM , Rating: -1
Fact: Africans are the solitary progenitors of all "humans". Neanderthals and ... "us Modern Humans" aka Modern Africans have the same progenitor from Africa. Modern Africans left the continent met with some Archaic Africans and had sex with them, producing African/African hybrids. The end... Any Questions? You Euro/Asian ... Africans should forgo your authoritarian-supremacist societies bullshit and blood lust. Embrace the fact that your ancient African ancestor never gave up and for millions of hard years carried your Genes. Shit ... for one minute some recessive skin/hair gene found footholds in foreign lands for this alone your going crazy and dising your exploited brothers and sisters.




By mstrmac on 8/27/2011 6:59:23 PM , Rating: 2
Well about 6000 years ago the Adamic dna was introduced (one who can show red or blood/blush in their flesh) formed somewhat different then the homo sapiens 12000/15000 years ago who were hunters and fisher nomads nevertheless. Now i am sure those earlier dispersed humans did their thing amongst the Neanderthals and whatever. but you can easily find pure adamic humans around. Also just because there is a link with africa does not mean the skin was dark.


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