Researchers Kill Cancerous Tissue with Hyperthermia
November 23, 2010 1:53 PM
comment(s) - last by
Virginia Tech and Jadavpur University researchers use what they are calling Thermotherapy to kill cancerous tissue
Engineering researchers at
have found that cancerous cells can be pinpointed and killed through the
use of hyperthermia
The lead researchers of the study includes Monrudee Liangruksa, a Virginia Tech graduate student in engineering science and mechanics; Ishwar Puri, professor and head of the department, and Ranjan Ganguly, of Jadavpur University's Department of Power Engineering in Kolkata, India. Together, these researchers have found a way to utilize hyperthermia as a way of elevating the temperature of tumor cells while making sure the healthy tissue surrounding these cells stay at a lower temperature.
To do this, the research team
induced the hyperthermia
using ferrofluids, which are liquids that become heavily magnetized when in the presence of a magnetic field. Through the use of ferrofluids, magnetic nanoparticles are "suspended" in the non-polar state.
"These fluids can then be magnetically
targeted to cancerous tissues
after intravenous application," said Puri. "The magnetic nanoparticles, each billionths of a meter in size, seep into the tissue of the tumor cell due to the high permeability of these vessels."
Researchers then expose the tumor to a high frequency alternating magnetic field, which heats the magnetic nanoparticles and results in the death of the tissue. They used temperatures between 41 and 45 degrees Celsius, which is enough to stop the growth of cancerous tissue.
The process this research team used is called magnetic fluid hyperthermia, but they are calling it thermotherapy. Thermotherapy was necessary in the study because temperatures of 41 to 45 degrees Celsius can also kill healthy tissue in addition to the cancerous tissue. Thermotherapy insures that healthy tissue stays at lower temperatures.
"The ideal hyperthermia treatment sufficiently increases the temperature of the tumor cells for about 30 minutes while maintaining the healthy tissue temperature below 41 degrees Celsius," said Puri. "Our ferrofluid-based thermotherapy can be also accomplished through thermoablation, which typically heats tissues up to 56 degrees Celsius to cause their death, coagulation, or carbonization by exposure to a noninvasive
, alternating current magnetic field. Local heat transfer from the nanoparticles increases the tissue temperature and ruptures the cell membranes."
The next step is to test their analytical approach on several different cancer cells by conducting experiments along with Dr. Elankumaran Subbiah from the Virginia-Maryland School of Veterinary Medicine.
was presented at the 63rd annual meeting of the
American Physical Society
on November 23.
This article is over a month old, voting and posting comments is disabled
Hyperthermia? What's that?
11/25/2010 3:06:52 AM
Interesting to note that nobody picked up on the spelling mistake. For the record, it's Hypothermia
RE: Hyperthermia? What's that?
11/28/2010 2:48:56 AM
Hyperthermia, commonly called fever is higher than normal (hyper) temperature (thermia)
Hypothermia, is lower than normal (hypo) temperature (thermia)
Inducing fever is a hyperthermic treatment.
An ice bath is a hypothermic treatment.
This treatment exposes selected tissues to extreme heat...hence localized hyperthermia.
Ice cubes applied to bruises and burns expose selected tissues to extreme cold...hence localized hypothermia.
An extreme form of cold treatment is cryotherapy where materials like dry ice or liquid nitrogen are applied to the tissues in question. This burns the tissue with extreme cold :)
I hope that clears things up for you.
"Intel is investing heavily (think gazillions of dollars and bazillions of engineering man hours) in resources to create an Intel host controllers spec in order to speed time to market of the USB 3.0 technology." -- Intel blogger Nick Knupffer
New Portable, Radio Frequency Scanner Detects Breast Cancer in Seconds
October 27, 2010, 11:39 AM
Critical Patients in Boston Could be "Frozen" Before Surgery
September 29, 2010, 5:13 PM
New MIT Nanotech Fights Cancer Naturally
September 20, 2010, 8:30 AM
Creationists are Mad About Google Doodle Depicting Evolution
November 24, 2015, 8:48 PM
DHS and TSA: Whoops, We Missed That 73 Airport Employees May be Terrorists
November 19, 2015, 2:16 PM
Star Wars Spinoff Film "Rogue One", Theme Park Attractions Announced
August 17, 2015, 12:20 PM
SpaceX Falcon 9's Seventh Supply Mission to ISS Ends w/ Fiery Stage 1 Explosion
June 28, 2015, 1:10 PM
Cool Science Video: Glowing Millipede Prowls the Nevada Desert
May 18, 2015, 12:00 PM
Newly Discovered Costa Rican Glass Frog is Kermit's Doppelgänger
April 22, 2015, 11:26 AM
Latest Blog Posts
Sceptre Airs 27", 120 Hz. 1080p Monitor/HDTV w/ 5 ms Response Time for $220
Dec 3, 2014, 10:32 PM
Costco Gives Employees Thanksgiving Off; Wal-Mart Leads "Black Thursday" Charge
Oct 29, 2014, 9:57 PM
"Bear Selfies" Fad Could Turn Deadly, Warn Nevada Wildlife Officials
Oct 28, 2014, 12:00 PM
The Surface Mini That Was Never Released Gets "Hands On" Treatment
Sep 26, 2014, 8:22 AM
ISIS Imposes Ban on Teaching Evolution in Iraq
Sep 17, 2014, 5:22 PM
More Blog Posts
Copyright 2016 DailyTech LLC. -
Terms, Conditions & Privacy Information