Print 34 comment(s) - last by Denithor.. on Jul 22 at 10:18 AM

  (Source: blogmodart)

  (Source: crtv)
Could contribute an almost 30-year campaign against AIDS

Researchers may have found a HIV preventative gel, which contains an AIDS drug already on the market, that could decrease a woman's chances of getting HIV in half. It was announced at the International AIDS Conference in Vienna, but further testing is required to make sure the product is safe and effective. 

AIDS has claimed 25 million lives total, and 33 million more are infected by HIV. Of this total, two-thirds are from sub-Saharan Africa. In this area, 60 percent of new infections develop among women and young females. 

For years, the only way to prevent HIV infection was by the use of condoms and male circumcision, since the foreskin contains cells that are "vulnerable to penetration by HIV." But the latter only prevents HIV infection in males. 

The study was led by Quarraisha Abdool Karim and Salim Abdool Karim from the Centre for the AIDS Programme of Research in South Africa (CAPRISA) in Durban. It consisted of almost 900 South African women who were sexually active and between the ages of 18 and 40, where 444 received a placebo and 445 received the microbicide gel. It was conducted in both the urban setting of Durban and the rural setting of Pietermaritzburg in the KwaZulu-Natal province.

Over a three year period, these women were asked to apply the gel, which contains a mixture of antiretroviral drugs and a one percent formulation of tenofovir that interrupts the reproduction of HIV in immune cells, with a vaginal applicator within a 12 hour window before intercourse and within a 12 hour window after intercourse. They were then tested for HIV on a monthly basis. In comparison to the placebo group, those who used the microbicide reduced the risk of HIV by 39 percent overall. For those who used the microbicide more often, as directed, 54 percent of the risk of HIV was reduced. 

"Without this gel, we may see 10 women becoming infected in a year," said Salim Abdool Karim. "With this gel, we would see only six women becoming infected."

While no major side effects were observed over the course of the study, the gel did become less effective after 18 months of use, and researchers are looking into finding out why. Right now, they believe it may be due to the fact that 40 percent of the women "used the microbicide less than one time out of two." Also, they will continue testing the gel to make sure there are no long term side effects that will exist beyond a three year period. 

The study has been published in the journal Science and could prove to be a vital part of finding efficient, preventative ways to avoid HIV infection everywhere.

Comments     Threshold

This article is over a month old, voting and posting comments is disabled

RE: Influencing bad behavior?
By abscode on 7/20/2010 9:28:23 PM , Rating: 5
Yea, because every tribal community and village has a Kwik-E-Mart with a condom machine in the bathroom.

You also need to restrain from putting western sensibilities in the situation; in many communities the women do not have the right to say no to their husband's advances. So if their husband gets some strange on the side and becomes infected, she has zero ability to defend herself from the same fate. This gel can help change that.

RE: Influencing bad behavior?
By ZachDontScare on 7/21/2010 2:44:44 PM , Rating: 2
Basic health knowlege is not 'western sensibilities'. Condoms prevent HIV very well. This gel only resists it. That is not a sensibility, that is fact. If the Africans want to continue to commit mass suicide by ignoring this, then maybe we ought to stop thinking about imposing 'western sensibilities', and start telling them to stop letting their 'african sensibilities' destroy their continent.

I do think this is a gread advancement, but I agree with some of the other posters - this may backfire and discourage condom use.

RE: Influencing bad behavior?
By abscode on 7/21/2010 3:54:39 PM , Rating: 2
That paragraph does not mention condon use; read it again. Hint: rape. You're arguing that rapers should all be good people and wear condoms when asked. You know that's not going to happen right?

RE: Influencing bad behavior?
By PrinceGaz on 7/22/2010 7:31:21 AM , Rating: 1
Yea, because every tribal community and village has a Kwik-E-Mart with a condom machine in the bathroom.

You clearleh have never visited those sort of communities otherwise you would know that is most definitely not the case.

"I want people to see my movies in the best formats possible. For [Paramount] to deny people who have Blu-ray sucks!" -- Movie Director Michael Bay

Most Popular Articles5 Cases for iPhone 7 and 7 iPhone Plus
September 18, 2016, 10:08 AM
Laptop or Tablet - Which Do You Prefer?
September 20, 2016, 6:32 AM
Update: Samsung Exchange Program Now in Progress
September 20, 2016, 5:30 AM
Smartphone Screen Protectors – What To Look For
September 21, 2016, 9:33 AM
Walmart may get "Robot Shopping Carts?"
September 17, 2016, 6:01 AM

Copyright 2016 DailyTech LLC. - RSS Feed | Advertise | About Us | Ethics | FAQ | Terms, Conditions & Privacy Information | Kristopher Kubicki