quote: Technically, nicotine is not significantly addictive, as nicotine administered alone does not produce significant reinforcing properties. However, only after coadministration with an MAOI, such as those found in tobacco, nicotine produces significant behavioral sensitization, a measure of addiction potential. This is similar in effect to amphetamine.
quote: Modern research shows that nicotine acts on the brain to produce a number of effects. Specifically, its addictive nature has been found to show that nicotine activates reward pathways—the circuitry within the brain that regulates feelings of pleasure and euphoria.
quote: If someone can show me any drug that vastly affects dopamine levels but is not have addictive properties, then I would be willing to agree with the article.
quote: But can they be psychologically addictive? YES. Pretty much anything that affects the reward pathway in the brain can become psychologically addictive.