New Nano-"Motherships" Help Further the Microscopic War on Cancer
September 16, 2008 10:15 AM
A rendition of the special lipid nanoparticle, the inside is composed of a mixture of superparamagnetic iron particles, fluorescent quandum dots and anti-cancer drugs. The lipid structure is coated with F3, a special cancer-seeking protein, to help it home in on cancer cells and deliver its payload.
(Source: Ji-Ho Park, UCSD)
Like a stealth jet, new nanoparticles evade the body's defenses while delivering chemical markers and lethal toxins to cancer tumors
Studying and developing treatments for cancer is possibly one of the most publicized fields in medical science in current times. There has been a deluge of new and promising treatments recently using
nano- and macro-scale particles
to, via the bloodstream,
deliver anti-tumor drugs
or anti-tumor weapons directly to the site of cancerous growths.
Building on past breakthroughs with these microscopic particles as drug ferries, a group of researchers from UC San Diego, UC Santa Barbara and MIT will shortly
publish new work
with a refined lipid-based transport system. While it is not the first lipid-based particle, it may be the first to be as robust as the researchers claim.
The specially engineered lipid structure, instead of simply carrying a toxin or heat bomb to cancer cells, is actually a multi-purpose unit. Coated with F3, a special cancer bloodhound protein, and filled with various imaging components (superparamagnetic iron nanoparticles for NMRIs and fluorescent “quantum dots” for fluorescence imaging) and anti-cancer drugs (doxorubicin), the tiny “motherships” were shown to evade the body's aggressive immune system for several hours while ferreting out cancer cells and delivering their payloads.
The structure is among the first to pack imaging and cancer killers in the same package. The success surprised even the researchers. Michael Sailor, a professor of chemistry and biochemistry at UCSD who headed the team of chemists, biologists and engineers, states, "The fact that the ships can carry very dissimilar payloads—a magnetic nanoparticle, a fluorescent quantum dot, and a small molecule drug—was a real surprise."
the Germany-based chemistry journal
The team is continuing to explore the possibilities of specialized coatings for the lipid transports. They are looking to develop more proteins that will seek out certain types of tumors or organs in the body and deliver their tailored cargo to those sites.
“Then they pop up and say ‘Hello, surprise! Give us your money or we will shut you down!' Screw them. Seriously, screw them. You can quote me on that.” -- Newegg Chief Legal Officer Lee Cheng referencing patent trolls
New Cancer Drug Delivery Cuts Tumor Targetting From Days To Hours
July 23, 2008, 2:23 PM
Polymer Nanoparticle Joins Cancer Killing Frenzy
July 10, 2008, 10:51 PM
Being worked to death? Study says high stress job and low job control can kill you
October 28, 2016, 4:44 AM
Birth Control Contributes to Depression in Teens and Young Women
October 26, 2016, 4:31 AM
Cyber Hackers Threaten Security of Lifesaving Medical Devices
October 19, 2016, 8:09 AM
Innovative Neurotechnology in Sound Therapy Reduces High Blood Pressure and Migraines
October 16, 2016, 5:00 AM
Researchers Move Closer to Breakthrough Gene Therapy to Cure Sickle Cell
October 14, 2016, 5:00 AM
Keytruda: A breakthrough treatment to increase survival rates for lung cancer patients
October 12, 2016, 5:00 AM
Most Popular Articles
Apple iOS Contains Secret One-handed Keyboard Code
October 22, 2016, 5:00 AM
The Unlocked Moto Z Play Launches for $449.99 Today.
October 22, 2016, 5:00 AM
The New HP Spectre: Revamped and Ready
October 23, 2016, 6:00 AM
New Way to Read Data on Ulta Hard Drives
October 23, 2016, 9:38 AM
Car Insurance - The Hidden Discriminatory Practise
October 18, 2016, 5:00 AM
Latest Blog Posts
From Time to Time, The Unbelievable and Unimaginable Happens!!!!
Oct 28, 2016, 4:56 AM
Key EpiPen Competitor Out in 2017 At ' Very Low' Cost
Oct 27, 2016, 5:30 AM
Researchers use CRISPR to Accelerate Search for HIV Cure
Oct 26, 2016, 5:00 AM
Medical Council of India Makes Generic Medicines Mandatory
Oct 25, 2016, 5:00 AM
MacBoo Pro 2016: Release date Oct. 27
Oct 24, 2016, 7:16 AM
Mac Users, Try this if Your Mac is Infected?
Oct 23, 2016, 7:00 AM
Tips to Prevent Smartphones From Overheating:
Oct 22, 2016, 5:00 AM
Nasa Flies Drones at Nevada Airport
Oct 21, 2016, 8:21 AM
T-Mobile Data Problems
Oct 20, 2016, 10:17 AM
Annoying Apple Watch Problems and How to Fix Them
Oct 20, 2016, 5:00 AM
Your Mail May Soon Be Delivered By Robot
Oct 19, 2016, 9:34 AM
2018 Jeep Wrangler Prototype Sells At Junkyard
Oct 18, 2016, 5:00 AM
Samsung Shines with Gold Edition Tablet
Oct 17, 2016, 9:24 AM
Tesla Hints Mysterious Product Debut for October 17th
Oct 16, 2016, 10:14 AM
Samsung Galaxy Note 7 Phones on US flights
Oct 15, 2016, 5:00 AM
Comcast Fined $2.3 Million For Unconfirmed Services Charged To Customers
Oct 14, 2016, 5:00 AM
“American singer / songwriter “Bob Dylan is awarded 2016 Nobel Prize in Literature.
Oct 13, 2016, 10:33 AM
More Blog Posts
Copyright 2016 DailyTech LLC. -
Terms, Conditions & Privacy Information