Scaffold protects the stem cells when implanted into living animals
Stem cell research is controversial,
but has the potential to find cures and treatments for a myriad of
diseases that are unaffected by current methods. Stem cells are being
heavily researched and scientists at the University of Hong Kong and
MIT have published a new study that outlines ways to keep stem cells
young and viable.
The research paper outlines a method that
promises to keep stem cells implanted in the body for treatment of
various conditions "forever
young." The new process can slow the growth of the stem
cells and the differentiation and proliferation of the stem
cells.
One of the paper authors, Dr. Ellis-Behnke said, "The
successful storage and implantation of stem cells poses significant
challenges for tissue engineering in the nervous system, challenges
in addition to those inherent to neural regeneration. There is a need
for creating an environment that can regulate cell activity by
delaying cell proliferation, proliferation, and maturation.
Nanoscaffolds can play a central role in organ regeneration as they
act as templates and guides for cell proliferation, differentiation
and tissue growth. It is also important to protect these fragile
cells from the harsh environment in which they are
transplanted."
New advancements in nanotech promise a new
era in tissue and organ construction according to Dr. Ellis-Behnke.
The researchers developed what they call a self-assembling nanofiber
scaffold (SAPNS) used for implanting young cells.
The team
used a scaffold that they created as a substrate for stem cell
adhesion and migration. This helped the stem cells survive once
implanted and helped prevent the invasion of cells from the
surrounding tissue. The goal of the SAPNS is to slow the growth and
differentiation of the implanted cells to give the cells time to
acclimate to the new environment. The researchers have been able to
use the technique to extend the life of cells implanted into the
brain and spinal cord of living animals.
Ellis-Behnke said,
"That delay is very important when the immune system tries
attacking cells when they are placed in vivo."
Scientists
and researchers have previously used stem cells to restore
the vision in a damaged eye and students embedded stem cells into
sutures to help promote
the healing of tendons after repair.
"The Space Elevator will be built about 50 years after everyone stops laughing" -- Sir Arthur C. Clarke
|
Most Popular ArticlesSpaceX Expected to Launch Dragon Capsule to ISS at 3:44am Tuesday Morning May 21, 2012, 10:13 PM New RAD Technique Allows DNA Sequences to Switch Back and Forth May 22, 2012, 4:20 PM Quick Note: Verizon Wireless Clarifies Stance on Unlimited LTE Data May 18, 2012, 8:08 AM Smartphone Giants Apple and Samsung Prepare for Settlement Talks May 21, 2012, 2:03 PM Analysts: Nokia Could be Out of Cash in Just a Year May 18, 2012, 5:26 PM
|