Bubbles are created inside a cell using lasers and nano-size gold particles
The
amount of money and time spent on research into treatments and cures
for various cancers is staggering. Scientists are increasingly
turning to high-tech methods of detecting and treating cancer that
use nano-sized objects to deliver meds and kill cancer cells
directly.
In October 2009, scientists developed a new
medication delivery system that is capable of delivering
medications into
the cells of the body. The “shuttle” would take the
medications into a cell and could be opened remotely when needed.
Physicists
at Rice University have developed a new method
of killing cancer cells using what they call
nanobubbles.
The research team uses lasers and nanoparticles
in a technique that is able to single out disease cells and destroy
them with tiny explosions. The nanobubbles are created by hitting
tiny nanoparticles of gold with a laser inside the cell. In
tests, the researchers found that they could tune the laser to make
bright visible bubbles that don’t kill the cancer cells or large
bubbles that bust the cells killing them.
Physicist Dmitri
Lapotko from Rice said, "Single-cell targeting is one of the
most touted advantages of nanomedicine, and our approach delivers on
that promise with a localized effect inside an individual cell. The
idea is to spot and treat unhealthy cells early, before a disease
progresses to the point of making people extremely ill."
The
nanobubbles are created when the gold particles are hit by short
laser pulses. The bubble size can be varied by controlling the
strength of the laser and the bubbles produced are very short lived.
The visible bubbles can be seen under a microscope allowing the
technique to be used as a method of diagnosing sick cells or to track
if the cells are killed with the tiny explosions. The researchers
have also been able to show that the technique can be used to clear
arteries blocked by plaque by busting the plaque with exploding
bubbles.
Lapotko said, "The bubbles work like a
jackhammer."
The researchers are currently conducting a
study using the technique to study its effect on leukemia cells and
on cancers of the head and neck. The nanobubble technology may be
used to create a process dubbed theranostics where a single process
can detect and treat disease conditions.
"Well, we didn't have anyone in line that got shot waiting for our system." -- Nintendo of America Vice President Perrin Kaplan
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