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The old CT technique produces a hazy 3D image. The arrow is pointing to a tumor.  (Source: J Keyriläinen, M Fernández, M-L Karjalainen-Lindsberg, P Virkkunen, M Leidenius, K von Smitten, P Sipilä, S Fiedler, H Suhonen, P Suortti, and A Bravin)

The new ABI technique, pictured here, produces a much sharper image, in which the easily missed tumor is instantly recognizable.  (Source: J Keyriläinen, M Fernández, M-L Karjalainen-Lindsberg, P Virkkunen, M Leidenius, K von Smitten, P Sipilä, S Fiedler, H Suhonen, P Suortti, and A Bravin)

Sabadell University researcher Alberto Bravin is among the researchers who helped develop the way of getting crisp views of the breast, like they'd never before seen.  (Source: J Keyriläinen, M Fernández, M-L Karjalainen-Lindsberg, P Virkkunen, M Leidenius, K von Smitten, P Sipilä, S Fiedler, H Suhonen, P Suortti, and A Bravin)
New research allows scientists to see breasts as they never have before, in order to ferret out cancer.

There's lots of exciting new research in breast cancer reduction.  First, a technique to produce 3D breast X-rays was developed to help researchers spot tumors they might otherwise have missed.  Then there was the slightly more questionable claim by a British researcher who claimed to have developed cancer-detecting bras.

Now there's world of another more technical exciting advance in breast cancer detection.  Researchers from Helsinki University Central Hospital, Turku University Central Hospital (Finland), the Radiation and Nuclear Safety Authority (Finland), the University Hospital of Grenoble (France), the European Molecular Biology Laboratory in Hamburg (Germany) and the Biomedical experimental station (beamline) at the European Synchrotron Radiation Facility (ESRF) have developed a new 3D scanning technique that will allow significantly higher resolution images than traditional X-rays.

Traditional breast cancer checks with X-rays fail to detect 10 to 20 percent of breast cancer, due to the fact that some women, particular younger women have denser breast tissue.  More accurate results are possible with X-ray computed tomography (CT) -- 3D X-ray scans, as discussed in the prior article here at DailyTech.  The problem with CT is that its accuracy is dependent on the dose of radioactive tracer used, and the breast is extremely radiosensitive -- in other words the scan to fix breast cancer, could cause cancer.  Thus CT scanning is limited to only use on tissue samples.

The researchers developed a new CT technique, which allows the researchers to view the breasts at unprecedented resolutions.  Not only that, but it did it all with clinically acceptable doses.  The new technique, dubbed Analyzer-Based X-ray Imaging (ABI) is expected to soon be able to be used in vivo (on a patient's living body).  Its accuracy was verified by a preliminary in vitro (tissue sample) test on a woman at the ESRF.

The new technique only requires one quarter of the radioactive tracer as tradition CT, while delivering 7 times the spatial resolution.  The woman in the trials had lobular carcinoma (a diffusely growing cancer) a special type of hard-to-see cancer that X-ray mammograms and ultrasonographs typically miss.  With the advances scans, the researchers were able to zoom in on previously unrecognizable details.

Describes Jani Keyriläinen, main author of the paper, "We can clearly distinguish more microcalcifications -small deposits of minerals which can indicate the presence of a cancer- than with radiography methods and improve the definition of their shapes and margins.  If we compare the images with X-ray mammograms and conventional CT images, we can confirm that this technique performs extremely well."

Alberto Bravin explains one problem of deploying an in vivo version in clinics stating, "The technique does not require sophisticated and expensive synchrotron radiation facilities.  (However) it would not be viable to use X-ray tubes, as exposure times would be too long and this would be incompatible with clinical practice."

With researchers close to achieving commercial compact high-energy X-ray generators, such as the experimental tabletop X-FEL machine of the Munich Advanced Center for Photonics- MAP, the new technology may be able to be performed on living tissue.  The development of high power X-rays is the key, as traditional ones take too long, and would still be hazardous.

Despite the disclaimer, Mr. Bravin says the new technique is much safer and more accurate than the previous CT method.  He states, "With these machines (high power X-rays) it would definitely be possible to apply this technique to clinical practice and, in this way, contribute actively to a more efficient detection of breast cancer."

The research is reported in the most recent edition of the journal Radiology.



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Disappointed
By bighairycamel on 9/18/2008 10:52:58 PM , Rating: 5
I have to admit, I only opened this article hoping to see a different brand of 3d images than the ones posted. . .

Don't judge me, I doubt I was the only one.




RE: Disappointed
By dflynchimp on 9/18/2008 11:21:00 PM , Rating: 4
I wasn't so much expecting pictures of actual mammaries as I was the deluge of wisecracks that usually follow in the thread. Don't get me wrong, I love them!


RE: Disappointed
By jtemplin on 9/19/2008 12:52:57 AM , Rating: 1
I'm all for cracking wise.

Best sub title evar:
quote:
New research allows scientists to see breasts as they never have before


It is in fact true...many scientists have never seen a breast before

Ziiiing!


RE: Disappointed
By Mitch101 on 9/19/2008 7:17:52 AM , Rating: 2
The sub title should have ended earlier.
quote:
New research allows scientists to see breasts


Seriously congrats to the guy who is saving them.


Genius
By icanhascpu on 9/18/2008 7:13:26 PM , Rating: 2
I needs to find me a box to make my own mammogram checkpoint.




RE: Genius
By amanojaku on 9/18/2008 7:17:51 PM , Rating: 2
I was thinking drive-through windows and home visits.


RE: Genius
By bobny1 on 9/18/2008 7:56:19 PM , Rating: 2
Poor Alberto can probably get a decent haircut now he is done with the research...LOL


RE: Genius
By Fnoob on 9/18/2008 8:52:52 PM , Rating: 2
Then maybe he would have a chance at a crisp view of a breast.

"Alberto Bravin is among the researchers who helped develop the way of getting crisp views of the breast, like they'd never before seen"


RE: Genius
By menace on 9/19/2008 2:19:03 AM , Rating: 2
I wonder how he got his test subjects. He must have pulled that "If you won't do it for me, then at least do it for Science" line.


Some people
By Fronzbot on 9/18/2008 8:56:10 PM , Rating: 1
You know, there are some people who should never have their pictures taken. This guy happens to be one of them.




RE: Some people
By Jedi2155 on 9/18/2008 10:04:21 PM , Rating: 2
I don't see anything wrong with him...he is a scientist after all....


RE: Some people
By SonicIce on 9/19/2008 12:37:10 AM , Rating: 2
lol
whens the last time that guy took a shower?


RE: Some people
By CyberHawk on 9/19/2008 5:40:50 AM , Rating: 2
He contributed A LOT.

And, not to mention, showered or not, he is a lot smarter then you are ;)


RE: Some people
By dice1111 on 9/19/2008 9:53:46 AM , Rating: 2
I think this line of work his is only access to breasts...


Breasts
By Fnoob on 9/18/2008 8:50:41 PM , Rating: 1
Should always be 3D.




RE: Breasts
By Fnoob on 9/19/2008 2:12:18 PM , Rating: 4
Whoever downrated that is clearly a flat-chested bull dyke lesbian.


I laughed quite loudly
By Howard on 9/20/2008 2:51:08 AM , Rating: 2
Alberto Bravin is among the researchers who helped develop the way of getting crisp views of the breast, like they'd never before seen.




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