backtop


Print 20 comment(s) - last by silentwriter.. on Aug 30 at 5:43 AM


severe jaw deficiency   (Source: borntosmile.com)
The stem cells, which are tissue repair cells called ixmyelocel-T, are used to re-grow craniofacial tissue

Humans with jawbone deficiencies in need of dental implants could benefit from a new stem cell trial conducted by Michigan researchers. 
 
Darnell Kaigler, study leader from the University of Michigan School of Dentistry, along with William Giannobile, co-author and director of the Michigan Center for Oral Health Research, and Aastrom Biosciences Inc. collaborated to create a stem cell-based method for bone regeneration. 
 
"In patients with jawbone deficiencies who also have missing teeth, it is very difficult to replace the missing teeth so that they look and function naturally," said Kaigler. "This technology and approach could potentially be used to restore areas of bone loss so that missing teeth can be replaced with dental implants."
 
The stem cells, which are tissue repair cells called ixmyelocel-T, are used to re-grow craniofacial tissue. They are taken from bone marrow from the patient's own hip and grown using Aastrom Biosciences Inc.'s proprietary system. 
 
To put ixmyelocel-T to the test, the team conducted a human trial where 24 patients with jawbone deficiencies and missing teeth were split into two groups: one that received the stem cell treatment, and the other that received convention bone regeneration treatment. 
 
The stem cells were placed into the mouth and jaw. Patients were observed after six and 12 weeks, and according to the results, those receiving the stem cell treatment experienced faster bone repair and greater bone density than those with traditional bone therapy. Also, the stem cell group required less secondary bone grafting for implants. 
 
This type of treatment could be used for those born with defects or those who've suffered trauma or certain diseases. However, more clinical trials are required before these stem cell therapies can be used regularly. 

Source: Eurekalert



Comments     Threshold


This article is over a month old, voting and posting comments is disabled

Another Adult Stem Cell Win
By kamiller422 on 8/1/2012 6:10:23 PM , Rating: 4
Not sure why article has link to embryonic stem cell research. It's an adult stem cell win.




RE: Another Adult Stem Cell Win
By aurareturn on 8/1/2012 6:42:33 PM , Rating: 5
Either way, we should pour government grant money into stem cell research.

Those religious heads will come along when they need the medical help.


RE: Another Adult Stem Cell Win
By KCjoker on 8/1/2012 7:27:58 PM , Rating: 1
Or we could use embryonic stem cells from umbilical cords and avoid the "issue" completely....nah Democrats want to keep the issue alive rather than solve the problem easily.


RE: Another Adult Stem Cell Win
By tjcinnamon on 8/1/12, Rating: -1
RE: Another Adult Stem Cell Win
By geddarkstorm on 8/1/2012 9:41:53 PM , Rating: 2
Or, we could just use your own adult stem cells to naturally repair your own tissue, instead of injecting cells with an entirely different genome (and a propensity to go cancerous, generate alternate tissue populations, be a target for your immunesystem) into your body. Best yet, no issues of supply since you carry all those regenerative potential cells right there in you. Hey look, everyone's problem is solved. Thanks science.


RE: Another Adult Stem Cell Win
By Tyndel on 8/1/2012 10:44:12 PM , Rating: 2
Adult Stem cells are where research should be pointed. I work with a guy who had cancer they did chemo then injected him with his bothers stem cells and he got his immune system back along with his brothers shell fish allergy. It was much like an organ transplant as far as rejection concerns.

The tech right now points at adult stem cells as being viable cures for many things right now and points at embryonic as maybe someday but not now unless you want complications....


RE: Another Adult Stem Cell Win
By FITCamaro on 8/2/2012 12:04:18 AM , Rating: 2
Christians largely have no issue with stem cell research as long as you're not murdering the unborn to get the cells.

But hey just keep up that hate.


RE: Another Adult Stem Cell Win
By FITCamaro on 8/2/2012 12:06:41 AM , Rating: 1
Let me also add or creating embryos just to harvest stem cells from them. Amounts to the same thing and essentially treating humans as cattle. Growing what we need and discarding the rest.

Maybe you have no morals but some people do.


RE: Another Adult Stem Cell Win
By JKflipflop98 on 8/2/2012 2:31:59 AM , Rating: 3
. . . so it's totally moral to do it to cattle but not humans why?


RE: Another Adult Stem Cell Win
By FITCamaro on 8/2/2012 11:58:57 AM , Rating: 2
Because cattle are not human beings and are not a self-aware being. Now you show me a cattle that makes decisions about its life and that has self-awareness, and we'll talk.

If you view cattle and humans at the same level, well then I really don't want you in charge of anything my life might in any way be connected with.


RE: Another Adult Stem Cell Win
By geddarkstorm on 8/2/2012 1:16:30 PM , Rating: 2
Because cows are delicious, that's why.


By MrBlastman on 8/2/2012 2:41:37 PM , Rating: 2
That they are!

A little OT but I think I'll share anyways: I made an awesome skillet burger last night and it is so easy any red-blooded Man should know how to do this.

It works best with frozen hamburger which you thaw, then start to pre-heat a frying pan/skillet with a nice lump of coconut oil plopped in it so it melts nicely, coating everything. (Coconut oil isn't nearly as bad for you as you'd think--well, the theory suggests at least).

You then make your patties and put them in the pan and sprinkle a nice amount of salt on them, covering with a lid afterwards. Let them cook for a few minutes (about five or six) on medium-low heat (I never get close to medium as they'll burn), then flip. After you flip, pour some more salt on them and cook for about two to three minutes. Add cheese (American is awesome), turn off the heat and let it melt, soaking in.

Done. Put on a bun (preferrably lightly toasted) and whatever else you'd like. Awesome, unhealthy goodness right there!

Thanks cows!

What's the whole point of this?

Well, simple, you wouldn't go next door chop up your neighbor, put them through a meat grinder, freeze them, thaw it back out and make a juicy burger using their meat, would you? If so... you need help, serious help.

Thus, cows are different from humans... in an edible, sane sense.


By conquistadorst on 8/2/2012 9:08:33 AM , Rating: 2
Not to mention any hypothetical embryonic stem cell industry would be a virtual dead end at some point. I venture to say in 50 years stem cell therapy will be so common that each person may receive treatment several times a year, probably even for arbitrary applications. What would we do? Take all of our teens and 20-somethings women and put them on conveyor belt and harvest their eggs for everyone's benefit? Yeah, it's sustainable but only until stem cell therapy becomes ubiquitous (which I'm looking forward to).

Also, there's unequivocally less risk associated with using one's own stem cells than those from a foreign body. With embryonic stem cells, with current tech, you're cursed for the remainder of your life of having a suppressed immune system due to immunosuppression drugs - not fun. Could you get away from having to use immunosuppression drugs? Possibly? Does any doctor consider it worth the risk of tissue rejection? Absolutely not...

And by the way, you have to be a numb nut to compare human beings to cattle on a moral level. Every animal deserves a certain level of respect, absolutely. I can wholeheartedly agree that we as a race don't give the respect to mother nature that is due but to suggest we're comparably the same is idiotic. Hey, why not compare us to cabbage and carrots too?


By shin0bi272 on 8/3/2012 11:12:36 AM , Rating: 2
um no dipshit. theres nothing in the constitution that allows for government money to be spent on scientific research. try to find it...go ahead.

Plus you apparently didnt read the part where it said "They are taken from bone marrow from the patient's own hip and grown using Aastrom Biosciences Inc.'s proprietary system."

The only stem cells we can make use of are our own. So killing unborn babies (dont know why liberals always wanna kill babies and save murderers... maybe you guys should just start wearing brown shirts and stop pretending to care about the defenseless) isnt going to do shit to help anyone.


Soo...
By Sanity on 8/2/2012 9:56:24 AM , Rating: 2
What's wrong with the woman in the before picture exactly? To me she just looks like she's un-attractive and had the bad fortune (and DNA) to be born with a weak chin. Are we calling having a weak chin a "jawbone deficiency" now? I've seen plenty of people like this and thought "Wow...they drew the short straw didn't they?", but never once did I realize this was some sort of medical malady. I kind of see this as nothing more than cosmetic surgery...using stem cells. The artical makes it seem much different than a cosmetic breakthrough. We all know where this is heading. Yep...breast and penis enlargment using stem cells. The one way they can be sure to turn a profit on their research.




RE: Soo...
By ipay on 8/2/2012 12:17:47 PM , Rating: 2
Look up the work of Weston A. Price, most dental/facial development problems are caused by nutrient deficiency in both the mother while pregnant and in the child's diet while growing. I would bet a million dollars that woman's facial development was not a genetic problem, but a lack of adequate nutrition in her and her mother's diet, especially Vitamin K2.

If all future mothers in America got enough Vitamin K2 in their diet starting today, and made sure their kids did as well, the dental industry would start to see a seriously huge drop in new young clients within the next couple decades...


RE: Soo...
By MrBlastman on 8/2/2012 2:46:46 PM , Rating: 2
I look at it and a lightbulb went off--"Oh, that explains the people who look like birds!"

It wasn't a major epiphany but nontheless, it makes me happy that there is now hope for them improving their odds of procreating. It sounds like it'd be less painful in the long run, also, being treated with stemcells and less surgery.


hesc...let's give them a chance!!!
By mbrom on 8/1/2012 10:37:57 PM , Rating: 3
we need to invest and study in adult AND embryonic stem cells.. adult stem cells have at least 20+ years of extra funding and studying than the more recently discovered embryonic stem cells. why would you want to inject your already mutated (and old) stem cells back into your body? the same cells that created the disease in the first place? there are companies out there (company called advanced cell technology) that pluck a SINGLE cell from a 6-8 cell early embryo allowing it to replicate (that's NATURE/science for you) and create an almost unlimited supply for humankind. Oh.. and the embryo that was used is NOT HARMED, since it can also replicate and continue growing. stem cells and their derivatives are the future.

10 people have been treated with ACT's embryonic stem cells, not one has cancer....plus Geron's embryonic cells..no cancer there either.




By geddarkstorm on 8/2/2012 1:33:23 PM , Rating: 2
Embryonic stem cells provide nothing that we don't have from adult stem cells, except problems. The vast majority of embryonic cells carry lethal mutations that prevent full embryonic development (that is, most conceptions fail, and we alive today are the lucky few). If a gene is defective in adult stem cells, it's simple to homologous recombine a fixed version in; trying to match an entire foreign genome is a very different thing.

Embryonic stem cells are not "more recently discovered", having been known since the 1960's. Adult stem cells are the recent discovery, as it was believed for ages that nothing but your liver, skin, and marrow could regenerate, but we've been finding more stem cells for different tissues (including the brain and heart) just this past decade. We can also now revert cells back to the pluripotent (embryonic like, minus the accessory cells that make the placenta) stage with incredible ease. Harvesting from embryos is never necessary, needlessly complex, offers complications and no benefits over our other methods.

ACT's trials are on going, and no results have yet been released; it's not complete. Geron halted its trial, for reasons unspecified, and have given up completely on such stem cell treatments (again, for reasons unspecified). See: http://stemcells.nih.gov/info/health.asp . Cancer takes years to appear, and none of these trials have been going more than months.


Deterioration of Maxilla
By silentwriter on 8/30/2012 5:43:22 AM , Rating: 2
I have complete deterioration of my Maxilla & John Hopkins advised me that taking bone from my hip wouldn't work either as they feel my body is attacking the bones in my mouth. They mentioned Stem Cell Research in the USA & said that the USA WILL NOT ALLOW IT TO BE DONE for dental purposes and now I've read this is NOT TRUE......I am confused, can someone help me? Thank you!




"If you mod me down, I will become more insightful than you can possibly imagine." -- Slashdot














botimage
Copyright 2014 DailyTech LLC. - RSS Feed | Advertise | About Us | Ethics | FAQ | Terms, Conditions & Privacy Information | Kristopher Kubicki