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A cure for baldness could be the golden egg for big pharmaceutical companies

Men all around the world suffering from male pattern baldness should be ecstatic to hear that scientists believe within two years a cure for baldness will be on store shelves. While the cure may appeal mostly to men, the fix for thinning hair will likely be appropriate for women as well.

For people suffering from baldness, the follicles still make hair, but in smaller amounts compared to years past. The scientists say that hair gets shorter and shorter until the hairs are barely visible or don't break the surface of the skin.

According to scientists involved with the research, talks are already underway with pharmaceutical companies to make a product that would be a lotion designed to halt the effects of a single enzyme. Earlier this year, dermatologists from the U.S. announced that they had located an enzyme called prostaglandin D2 (PGD2) that is responsible for telling hair follicles to stop producing hair.
 
During the research, scientist George Cotsarelis, head of dermatology at Pennsylvania University, and his team determined that and 17 men participating in their study who had hair loss also had PGD2 levels were three times higher in bald spots than in areas producing hair.

According to the scientists, drugs designed to reduce the levels of PGD2 are already available on the market because that same enzyme has been implicated in asthma attacks.
 
There is no doubt that the market for such a product would be huge, as four out of five men will experience some degree of baldness by age 70.

Source: Telegraph





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So....
By morgan12x on 5/22/2013 8:44:52 AM , Rating: 5
Could you make a lotion that has a ton of this enzyme to make a kick ass hair removal product?




RE: So....
By karimtemple on 5/22/2013 9:11:53 AM , Rating: 2
DEAR GOD YES


RE: So....
By cmart on 5/22/2013 9:12:26 AM , Rating: 5
Yes, but it gives you asthma.


RE: So....
By GulWestfale on 5/22/2013 9:16:25 AM , Rating: 1
hair removal creams already exist (veet, for example). i use them regularly, but as they are acid-based, it isn't recommended to use them on one's head or genital area. so i still own a razor...

as for a "cure" for baldness: i never knew baldness was a disease.


RE: So....
By cmart on 5/22/2013 9:21:46 AM , Rating: 5
It is a common and disfiguring disease. I can show you before and after pictures that are more harrowing than 'faces of meth.'


RE: So....
By Asetha on 5/22/2013 9:39:29 AM , Rating: 2
I used Veet on my brother during his bachelor party. We got him extremely drunk, and when he passed out we put Veet all over 1 of his legs, and left the other alone.

He looked awesome on the beach during his honeymoon.


RE: So....
By SeeManRun on 5/22/2013 10:33:30 AM , Rating: 2
It isn't a disease. It's a disorder which can be cured or treated like diseases can.


RE: So....
By Jeffk464 on 5/22/2013 10:38:17 AM , Rating: 2
quote:
as for a "cure" for baldness: i never knew baldness was a disease.


Hair has a purpose, it keeps your head warm during the winter and keeps your head from from getting fried in the summer.


RE: So....
By BRB29 on 5/22/2013 11:31:36 AM , Rating: 2
also protect you from damages and impacts.


RE: So....
By Argon18 on 5/28/2013 10:25:12 AM , Rating: 2
It also keeps the testes warm.


RE: So....
By Azethoth on 5/23/2013 12:37:48 AM , Rating: 5
That's why Prescott Pharmaceuticals mixes in an asthma cure as well. Side effects include: whooping hairball cough, dense jungle butt and palm dreadlocks.


RE: So....
By SilthDraeth on 5/22/2013 9:29:18 AM , Rating: 2
I love hair growth treatments.

"Lets spend money on a product that makes me grow hair again, so that I may spend money on products to remove the hair, either by myself, or paying another to remove and style.

I welcome not having to get hair cuts, as it saves me money and time.


RE: So....
By karimtemple on 5/22/2013 10:48:06 AM , Rating: 3
Styled hair vs. comical juxtaposed patches of pathetic growth and baldness.


RE: So....
By Souka on 5/22/2013 12:47:27 PM , Rating: 3
It's called "a first world problem"


RE: So....
By boobo on 5/22/2013 10:22:58 PM , Rating: 2
Yes, personal grooming is so unheard of in the 4th world. Oh, wait; they actually invented tattoos and piercings, among other things.


RE: So....
By ppardee on 5/22/2013 2:10:56 PM , Rating: 2
Seriously... I'd rather have a cure for partial baldness... My hair decided to start abandoning ship when I was 16 and about 5 years ago it decided it had had enough... I have not enough hair to do anything with.... I wish it to be gone already.

I can't imagine why anyone would want hair on their head... It was a quaint concept when I was young, but it just gets in the way now.


RE: So....
By Strunf on 5/23/2013 7:48:58 AM , Rating: 2
You save on hair cuts... just to spend money on sun protection or cold protection.


RE: So....
By Fidget on 5/23/2013 12:52:29 PM , Rating: 2
Do you also welcome women not checking you out?


RE: So....
By Bad-Karma on 5/22/2013 1:06:08 PM , Rating: 1
Where's the cure from cancer? Reminds me of the cigar-smoking lab monkey with a well developed Jheri curl and a giant erection from idiocracy?

Priorities........


RE: So....
By Motoman on 5/22/2013 2:11:21 PM , Rating: 4
Yes, because clearly the fact that we have a "cure" for baldness now means that no one cares about or is working on cancer remedies.


BFD
By rdhood on 5/22/2013 8:49:18 AM , Rating: 4
The pharmaceutical industry has been promising this for years. Every time they have a product that will grow hair on a billiard ball, we find out that it works on some small single digit percentage of men.... kind of.

IOW, we have heard this song and dance before. I'll believe it when it happens.




RE: BFD
By Reclaimer77 on 5/22/2013 9:09:40 AM , Rating: 3
Hey I'm glad they're working on it.

My crows nest started thinning in my late 20's! Now I have to keep my head shaved, which is a pretty rockin' look, but still...it would be awesome to have my thick curly 'guido' hair back.

If they've truly identified this compound as the culprit to hair loss, fantastic! Finding the problem is step 1, step 2 is fixing it.


RE: BFD
By Spuke on 5/22/2013 10:04:14 AM , Rating: 2
Me too! I'm just starting to thin out in the front. It would be awesome to stop it just as it's getting started.


RE: BFD
By Cheesew1z69 on 5/22/2013 11:31:23 AM , Rating: 2
I knew someone who went bald by 16... it was pretty crazy.


RE: BFD
By FF22 on 5/22/2013 9:10:29 AM , Rating: 1
The worst is: the pharmaceutical probably already has a cure for baldness, for decades now. The problem is: the pharmaceutical industry isn't interested in providing a cure. It's interested in providing a treatment. And that's the hard part: provide some drug, that when applied regularly treats the condition, but when stopped also let's the condition to return. That's why most drugs in this area fail. And that's why drugs are called drugs. Because they're supposed to be addictive, thus guaranteeing continous profit for the meg pharm corps.


RE: BFD
By Kurz on 5/22/2013 9:17:12 AM , Rating: 3
Links?


RE: BFD
By 91TTZ on 5/22/2013 9:26:19 AM , Rating: 5
Yeah, I'm sure they keep it right next to the cure for AIDS and Moon landing hoax tapes.

Save your lame conspiracy theories for another forum.


RE: BFD
By Strunf on 5/23/2013 7:58:20 AM , Rating: 2
The thing is baldness is probably mostly genetic so unless you start speaking of genetic therapy there will never be a permanent cure but only temporary fixes, even in this case it will probably be something that works on that specific enzyme but since we keep producing it chances are we would need to apply the treatment on a daily/weekly bases.

It's true the pharmaceuticals are more interested in thing temporary fixes however if the find a permanent fix they will sell it anyways, this cause if you have found it someone else may find it too and you may end up being caught off guard.


Meh!
By Bostlabs on 5/22/2013 10:28:49 AM , Rating: 3
I no longer care.

My hair has been steadily on the decline since my 20's. I'm in my 50's now and just shave, what little is left, off.

For the younger guys it may be something. But if is is just treatment, meaning like forever, it may not be worth the cost.




RE: Meh!
By fic2 on 5/22/2013 1:27:32 PM , Rating: 2
Mine started going in my 30s. In my 50s now and shave it. My gf said that is why she was attracted to me. Her 9 yo daughter wonders why I don't have hair (I tell her that I have to concentrate so it doesn't grow) and that I should grow it. Every time her mom says, "No!".

Anyway, I have even thought about laser treatment to permanently get rid of it but know that as soon as I do a cure/treatment will come out. Not sure that I would go for it (especially if it was a lifetime treatment) but would hate to have the option shut out.


RE: Meh!
By Lord 666 on 5/22/2013 2:45:35 PM , Rating: 2
Captain Jean-Luc Picard didn't care either... and they had the cure for a long time.


RE: Meh!
By rountad on 5/22/2013 3:12:22 PM , Rating: 3
Couldn't have been too long because Captain Kirk had a toupee!


RE: Meh!
By maugrimtr on 5/23/2013 11:24:42 AM , Rating: 2
Even Dr. House never figured out a cure. He spent 8 years making sure cameras never got a direct shot of the back of his head where a grey animal apparently died.


By CZroe on 5/22/2013 10:44:45 AM , Rating: 3
Hmm. A spammer necro'd a post on Anandtech's Off-Topic forum from last year about this and now it's the latest story on DailyTech.

forums.anandtech.com/showthread.php?t=2267887

Shouldn't it now say 1.25 years? :)




By AlphaVirus on 5/22/2013 11:32:33 AM , Rating: 2
Hahaha good catch.

The original article on The Telegraph makes no quote of "two years" from the study. I went further back to the actual study and the stupid website doesn't allow you to view anything without an account. From the abstract there is still no mention of two years. So I'd question the legitimacy of a two year promise, it could've been the original article reaching for hits.

Here is the very original study source.
http://stm.sciencemag.org/content/4/126/126ra34.ab...


Cure? or treatment...
By jwdR1 on 5/22/2013 10:10:51 AM , Rating: 2
It's been a long time since our medical industry has produced an actual cure for anything. I doubt seriously if they want to produce a 'cure' otherwise they will run out of patients in short order.

No, they'll end up producing a 'treatment' so we can pay for it for the rest of our lives. :(




RE: Cure? or treatment...
By Cape Consultant on 5/24/2013 2:59:38 AM , Rating: 2
Well said. Can anyone here name something that was "cured" by big pharma? Ever? Vaccines excepted. They are another story.


Already Exists
By rs2 on 5/22/2013 9:24:40 PM , Rating: 2
There's already a cure for baldness on the market. It's called finasteride. Been available for years.




RE: Already Exists
By Grimcube on 5/23/2013 6:31:53 AM , Rating: 2
Problem with finasteride is it's not safe, since it can cause permanent negative side effects.

Reported side effected related to finasteride include:
Erectile dysfunction (impotence)
Abnormal ejaculation
Lower ejaculatory volume
Abnormal sexual function
Testicular pain
Gynecomastia - development of male breasts
Depression


hair
By bosox04 on 5/23/2013 3:36:07 PM , Rating: 2
Cure for baldness? This is only going to help "somewhat" for people who just started losing their hair. This is not a cure for baldness. Besides, clinical trials will start in 2 years, it's not coming out in 2 years. Cure for baldness? Nah, should say Cure for early hair loss.




RE: hair
By kyleb2112 on 5/27/2013 12:49:14 AM , Rating: 2
Exactly. People with shiny-head baldness like George Costanza have no follicles up there left to treat.


Hair Transplant
By Flunk on 5/22/2013 9:04:21 AM , Rating: 2
If this does end up working it's going to make those guys who got the Frankenstein-style hair transplants feel really stupid isn't it?




By BRB29 on 5/22/2013 10:36:43 AM , Rating: 2
quote:
According to the scientists, drugs designed to reduce the levels of PGD2 are already available on the market because that same enzyme has been implicated in asthma attacks.


Now you can stop asthma and hair loss at the same time! Just rub that asthma medication on your head!




2 years from when?
By MattCoz on 5/22/2013 4:20:18 PM , Rating: 2
The date of that article is August 2012, so that means 1 year and 3 months from now? I'll believe it when I see it.




Back, crack, and sack
By ipay on 5/22/2013 6:12:20 PM , Rating: 2
Maybe they can do to opposite too. I'd love to have a way to stop the forest that has slowly been taking over my back.




will it work ...
By Heinrich on 5/22/2013 8:01:50 PM , Rating: 2
on my buttocks?




limited use
By Grimcube on 5/22/2013 9:00:56 PM , Rating: 2
From reading this article i assume this product will only help prevent future hair loss and not actually restore hair on an already bald head. There are loads of commercials for shampoo on TV already that advertise this so i don't believe this will be much different.




Electrolytes....
By petrosy on 5/23/2013 7:47:38 PM , Rating: 2
its what hair follicles need.




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