 An artist's depiction of the lipid-covered silicon nanowire device. Alamethicin molecules, shown as purple tubes, can be controlled by altering the voltage through the nanowire to let ions pass through the lipid boundry. (Source: Scott Dougherty, LLNL)
Mixing living cells with microscopic electronics may yield a new breed of processing power.
Though computer engineers and
scientists have been repeatedly breaking speed barriers with new
supercomputers, they still pale in comparison to the information
processing power of complex biological systems. IBM's Roadrunner
supercomputer, presently the fastest
in the world, has been used to mimic
a single part of brain function, the visual cortex, and that's
only a fragment of the information the human body processes at any
given moment.
So when researchers look to the future of
computing, attempting to mimic bio-functions or combine them with
electronics seems like a step in the right direction as far as speed
and efficiency are concerned. However, the reality of the situation
is not so supportive. Past attempts to merge the two types of systems
have not yielded any special results.
Lawrence Livermore
National Laboratory scientists are taking a deeper, or more
nanoscopic, look into the idea of cohabitating
the living and the inanimate. “With the creation of even
smaller nanomaterials that are comparable to the size of biological
molecules, we can integrate the systems at an even more localized
level,” explains Aleksander Noy, lead LLNL scientist on the
bio-electrical project.
To step into this realm of the
minutia, Noy's team turned to silicon nanowires and lipid membranes –
both popular ingredients in modern nanomaterials research. By
covering the silicon nanowire with a back-to-back layer of lipid
membranes, the scientists are able to isolate the conducting nanowire
from outside solutions. Just as in normal biological systems, the
lipids prevent ions and small molecules from reaching the
nanowire.
In order to create an pseudo information gateway,
the lipid layer is interspersed with alamethicin molecules, which act
as pores to allow information, in this case ions, to flow into and
out of the nanowire. By controlling the gate voltage being held by
the nanowire, the scientists can open and close the pore molecules,
either allowing ions to escape (signal transmission) or allowing them
to slip through the lipid wall (detection devices).
Nipun
Misra, a member of Noy's team and University of California at Berkley
graduate student adds to Noy's explanation, “That's not to mention
that these lipid membranes also can house an unlimited number of
protein machines that perform a large number of critical recognition,
transport and signal transduction function in the the cell.”
While
the small device is obviously not a fully functioning system, it does
create a working foundation for more research into bio-electrical
systems. If scientists could harness the speed and power of something
even remotely close to the human nervous system's, great leaps of
power might be realized in computing technology. Postulations towards
tiny fluid-borne microsensor systems based on this technology and
combined with the idea of the single nanowire transmission device
makes micromachines like medical nanobots less of a science fiction
contraption than a budding reality.
Noy, Misra and third
co-author Julio Martinez's, a graduate student at University of
California at Davis, research data can be found in the August 10th
Proceedings of the National Academy of Sciences online
edition
"If you look at the last five years, if you look at what major innovations have occurred in computing technology, every single one of them came from AMD. Not a single innovation came from Intel." -- AMD CEO Hector Ruiz in 2007
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